Avery Sonnenberg

Partner @ Two Bear Capital | PhD in Bioengineering

📍 United States🔄 Updated September 2026💼 3 investments📅 7 years investing🗓 Last invested Jul 2024
VC🌍 United States
3
Total investments
0
Early stage
2
Mid stage
0
Late stage
7y
Years active

Portfolio

3 investments · sorted by recency
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Late stage
Investor, Board Observer
Jul 2024
Talus Bio is making the regulome visible and druggable. We are building the first platform to map, model, and ultimately write the regulome, unlocking thousands of previously undruggable targets, including transcription factors that drive cancer, autoimmunity, and neurodegeneration. Our platform measures the regulome directly in living human cells, generating functional datasets at scale for the first time. These data fuel AI models that learn the logic of genome regulation and predict how to modulate it with precision.
Investor, Board Observer
Jun 2020
Inimmue is a new biotechnology company founded by pharmaceutical industry veterans focused on developing next generation immunotherapeutics.
Investor, Board Observer
Dec 2019
FYR is revolutionizing the ability to dynamically observe disease and treatment response to produce better biomarkers, trials, drugs and outcomes. FYR’s EV-Omics (EVO) platform leverages its proprietary technology, SPARCs, to enrich for extracellular vesicles from diseased cells and enable the deep assessment of proteins and nucleic acids from a simple blood draw. Utilizing AI-enabled multiomic insights, EVO unravels the complexity of disease mechanisms, thereby informing potential diagnostic and treatment options. The unparalleled view provided by FYR’s multiomic approach can transform personalized patient care, from screening through therapy selection and monitoring. For more, visit fyr.bio.
Experience · 5 entries
All (5)
Investments (3)
Board (3)
2024
Investor, Board Observer
Jul 2024
Talus Bio is making the regulome visible and druggable. We are building the first platform to map, model, and ultimately write the regulome, unlocking thousands of previously undruggable targets, including transcription factors that drive cancer, autoimmunity, and neurodegeneration. Our platform measures the regulome directly in living human cells, generating functional datasets at scale for the first time. These data fuel AI models that learn the logic of genome regulation and predict how to modulate it with precision.
2020
Investor, Board Observer
Jun 2020
Inimmue is a new biotechnology company founded by pharmaceutical industry veterans focused on developing next generation immunotherapeutics.
2019
Investor, Board Observer
Dec 2019
FYR is revolutionizing the ability to dynamically observe disease and treatment response to produce better biomarkers, trials, drugs and outcomes. FYR’s EV-Omics (EVO) platform leverages its proprietary technology, SPARCs, to enrich for extracellular vesicles from diseased cells and enable the deep assessment of proteins and nucleic acids from a simple blood draw. Utilizing AI-enabled multiomic insights, EVO unravels the complexity of disease mechanisms, thereby informing potential diagnostic and treatment options. The unparalleled view provided by FYR’s multiomic approach can transform personalized patient care, from screening through therapy selection and monitoring. For more, visit fyr.bio.
Principal
Nov 2019
Two Bear Capital is a venture capital firm that invests in entrepreneurs who have breakthrough ideas in life sciences and technology. Two Bear Capital’s vision is to build an ecosystem of support, economic opportunity and innovation that brings the most meaningful ideas to market in the form of enduring high-impact businesses that benefit society as a whole, while delivering for investors. The firm primarily focuses on early, founder-led companies with disruptive innovations in biotechnology, bioinformatics, healthcare IT, machine learning and AI, and information security. Two Bear Capital has offices in Menlo Park, San Diego, Boston, and New York, with its home base in Whitefish, Montana. It was founded in 2019 by Mike Goguen.
2016
Research Associate
Feb 2016
BD is one of the worlds largest pure-play medical technology companies with a Purpose of advancing the world of health™ by driving innovation across medical essentials, connected care, biopharma systems and interventional. The company supports those on the frontlines of healthcare by developing transformative technologies, services and solutions that optimize clinical operations and improve care for patients. Operating across the globe, with more than 60,000 employees, BD delivers billions of products annually that have a positive impact on global healthcare. By working in close collaboration with customers, BD can help enhance outcomes, lower costs, increase clinical efficiency, improve safety and expand access to healthcare. For more information on BD, please visit bd.com. See community guidelines here: https://tinyurl.com/yunjmzkx.
Investment activity
2019–2024 · 3 investments
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