Omri Amirav-Drory

General Partner at NFX

📍 Berkeley, California, United States🔄 Updated September 2026💼 29 investments📅 7 years investing🗓 Last invested Jul 2026𝕏 @upgrade_to_unlock
VC🌍 United States20+ investmentsInvested this quarter
29
Total investments
12
Early stage
2
Mid stage
1
Late stage
7y
Years active

Portfolio

25 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Board Member
Jul 2026
EarthTraq is building game-changing satellites for simple, secure global positioning.
Board Member
May 2026
Portal is building the universal infrastructure for cell engineering across drug discovery and cell therapy. Our proprietary mechanical system enables efficient, scalable delivery of RNA, gene editors, probes, and other molecules into hard-to-transfect cells across many cell types and workflows. With more than 100 customer sites including the top 10 pharma, researchers use Portal to run high-throughput, physiologically relevant screens and de-risk targets earlier, while cell therapy developers leverage the platform to multi-engineer cells beyond the limits of viral or electroporation methods. Integrated with leading high-throughput robotics and with GMP manufacturing systems, Portal is powering both next-generation discovery and laying the groundwork for future point-of-care cell therapy manufacturing.
Board Member
Dec 2025
Our mission is to cure endometriosis. We are a team of interdisciplinary scientists creating a new model in womens health research centred around an in depth understanding of tissue-level disease processes. We are committed to improving the quality of life of women by providing a new model for therapeutic discovery. We sit at the interface between tissue biology, computation and laboratory disease modelling.
Board Member
Apr 2025
ImmuneBridge is developing allogeneic immunotherapies for cancer. Our core technology drives the expansion of cord blood derived immune stem cells and establishes a novel, flexible, consistent and abundant cellular source for immunotherapies. We are currently pursuing natural killer cell products for hematological malignancies. Next we will use the unique advantages of our cellular source to tackle solid tumors. Platform ImmuneBridge is creating a platform of scalable allogeneic immune cell therapies from cord blood. Our proprietary technology, including a novel small molecule, expands cord blood HSPCs over 100,000-fold while maintaining full immune multipotency, with the ability to differentiate into cell types including NK cells, T cells and macrophages. Pipeline In the near term, our goal is to validate the economic and clinical benefits of our expansion technology by taking an expanded-HSC-derived NK cell to clinical trials for hematological malignancies. In the long term, our unique access to the modified and unmodified immune tree allows us to tackle the challenge of solid tumors with combinations of modified cells. Agile Discovery This agile and flexible allogeneic platform reduces costs of discovery and manufacturing, expanding commercially viable indications for cellular immunotherapy. Starting from cord blood has speed and cost advantages over iPSCs, including the ability to quickly match HLA types to target populations or select beneficial genotypes without the need to edit those features into a clonal iPS line. This enables rapid iterations of abundant and consistent sources of therapeutic cells.
Board Member
Mar 2025
At Powerhouse Biology, we pioneer precision peptide therapeutics to address mitochondrial dysfunction, an underlying driver of many age-related diseases.
Board Member
Feb 2025
We develop therapies to protect the genome.
Board Member
Mar 2024
TwoStep Therapeutics is pioneering a multi-targeting platform to advance a pipeline of targeted therapies that are broadly applicable across solid tumors. With this approach, the company aims to transform cancer treatment by extending precision medicines to more diverse tumor types and patient populations, for which few options exist. TwoStep Therapeutics was co-founded by CEO, Caitlyn Miller, in collaboration with world-renowned academic entrepreneurs at Stanford University: Jennifer Cochran, Ronald Levy, and Nobel Laureate Carolyn Bertozzi. For more information, visit www.twosteptx.com.
Board Member
Apr 2023
Compressing biology to develop the next generation of therapies
Board Observer
Oct 2022
Smash the mutants
Board Member
May 2022
Helping patients fight treatment-resistant cancer. resistanceBio can discover and overcome clinical treatment resistance pre-clinically.
Board Member
Jan 2022
Pumpkinseed enables life-speed reads of biological bits. We merge the power of silicon photonics and machine learning with state-of-the-art biochemistry for high-resolution protein sequencing. Genomics and transcriptomics have revolutionized how we diagnose and treat disease but it’s only part of the solution. Unraveling the proteome—and characterizing the breadth and dynamics of proteoforms—is critical to address many of the biggest challenges in personal, population, and ecosystem health. Rather than relying on sample amplification or fluorescent tags, we amplify light—and how light interacts in unique ways with each protein. Our method provides high resolution and quantitative insight into proteins, including their sequence, post-translational modifications, structure, and interactions. We strive to enable proactive solutions rather than reactive and crisis-based approaches, informing when to start treatment, which treatment is best, and how to design new therapies and vaccines. Solving the most challenging and impactful problems in medicine and sustainability will require a new lens into the inner working of cells. Come visit us to learn more, or get in contact with us about joining our team to build a better tomorrow with biology.
Board Member
Dec 2021
Talus Bio is making the regulome visible and druggable. We are building the first platform to map, model, and ultimately write the regulome, unlocking thousands of previously undruggable targets, including transcription factors that drive cancer, autoimmunity, and neurodegeneration. Our platform measures the regulome directly in living human cells, generating functional datasets at scale for the first time. These data fuel AI models that learn the logic of genome regulation and predict how to modulate it with precision.
Board Member
Oct 2021
Mana.bio is an AI based drug delivery startup, creating a platform for Lipid Nanoparticle (LNP) development for oligonucleotide therapies including mRNA-based therapeutics, vaccines and gene therapy.
Board Member
Oct 2021
La Jolla Labs is a privately held therapeutics company with research in high-throughput screening technology for rare disease drug discovery.
Show all 25 investments ↓
Experience · 34 entries
All (34)
Investments (29)
Founder (2)
Board (29)
2026
Board Member
Jul 2026
EarthTraq is building game-changing satellites for simple, secure global positioning.
Board Member
May 2026
Portal is building the universal infrastructure for cell engineering across drug discovery and cell therapy. Our proprietary mechanical system enables efficient, scalable delivery of RNA, gene editors, probes, and other molecules into hard-to-transfect cells across many cell types and workflows. With more than 100 customer sites including the top 10 pharma, researchers use Portal to run high-throughput, physiologically relevant screens and de-risk targets earlier, while cell therapy developers leverage the platform to multi-engineer cells beyond the limits of viral or electroporation methods. Integrated with leading high-throughput robotics and with GMP manufacturing systems, Portal is powering both next-generation discovery and laying the groundwork for future point-of-care cell therapy manufacturing.
2025
Board Member
Dec 2025
Our mission is to cure endometriosis. We are a team of interdisciplinary scientists creating a new model in womens health research centred around an in depth understanding of tissue-level disease processes. We are committed to improving the quality of life of women by providing a new model for therapeutic discovery. We sit at the interface between tissue biology, computation and laboratory disease modelling.
Board Member
Apr 2025
ImmuneBridge is developing allogeneic immunotherapies for cancer. Our core technology drives the expansion of cord blood derived immune stem cells and establishes a novel, flexible, consistent and abundant cellular source for immunotherapies. We are currently pursuing natural killer cell products for hematological malignancies. Next we will use the unique advantages of our cellular source to tackle solid tumors. Platform ImmuneBridge is creating a platform of scalable allogeneic immune cell therapies from cord blood. Our proprietary technology, including a novel small molecule, expands cord blood HSPCs over 100,000-fold while maintaining full immune multipotency, with the ability to differentiate into cell types including NK cells, T cells and macrophages. Pipeline In the near term, our goal is to validate the economic and clinical benefits of our expansion technology by taking an expanded-HSC-derived NK cell to clinical trials for hematological malignancies. In the long term, our unique access to the modified and unmodified immune tree allows us to tackle the challenge of solid tumors with combinations of modified cells. Agile Discovery This agile and flexible allogeneic platform reduces costs of discovery and manufacturing, expanding commercially viable indications for cellular immunotherapy. Starting from cord blood has speed and cost advantages over iPSCs, including the ability to quickly match HLA types to target populations or select beneficial genotypes without the need to edit those features into a clonal iPS line. This enables rapid iterations of abundant and consistent sources of therapeutic cells.
Board Member
Mar 2025
At Powerhouse Biology, we pioneer precision peptide therapeutics to address mitochondrial dysfunction, an underlying driver of many age-related diseases.
Show all 34 entries ↓
Investment activity
2019–2026 · 29 investments
2019620203202182022320231202422025420262
Recent (last 2 years)Earlier