Harsh P.

Managing Partner & Co-Founder at Wireframe Ventures

📍 Menlo Park, California, United States🔄 Updated September 2026💼 19 investments📅 22 years investing🗓 Last invested Apr 2023
VC🌍 United States
19
Total investments
9
Early stage
3
Mid stage
4
Late stage
22y
Years active

Portfolio

18 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Investor
Apr 2023
Tembo is the Postgres developer platform for building every data service. Our mission is to collapse the database sprawl of the modern data stack with a unified developer platform. With Tembo, developers can quickly create and deploy specialized data services using Stacks, pre-built Postgres configurations, and deployments without complex builds or additional data teams.
Investor
Apr 2021
Using microbes to drug the undruggable
Investor
Sep 2019
At Enveda, we are systematically translating molecules found in medicinal plants into new drugs for challenging diseases. Our platform harnesses natures complexity with the help of cutting-edge advancements in knowledge graphs, machine learning, and metabolomics.
Investor
Mar 2019
Endpoint Health is a Precision-First therapeutics company dedicated to addressing unmet needs in immune-mediated chronic and acute diseases. We leverage our proprietary artificial intelligence (AI) platform and combine companion diagnostics with therapeutics to develop precision therapies. Our vision is a world in which all patients get the best treatment possible for their unique biology and disease.
Investor
Mar 2018
Engineering next generation kinase inhibitors with computation.
Investor
Jan 2018
Mammoth Biosciences is a biotechnology company focused on leveraging its proprietary ultracompact CRISPR systems to develop long-term curative therapies, as well as other applications such as decentralized precision diagnostics. Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing. The company is building out its pipeline of potential in vivo gene editing therapeutics and capabilities and has partnerships with leading pharmaceutical and biotechnology companies to broaden the reach of its innovative and proprietary technology. Mammoth’s deep science and industry experience, along with a robust and differentiated intellectual property portfolio, have enabled the company to further its mission to transform the lives of patients and deliver on the full promise of CRISPR technologies.
Investor
Jun 2017
Misty Robotics is introducing a new way of entering the world of robotics. With Misty, a friendly and highly sophisticated educational robot platform, we are opening up access to robots in STEM education and research by taking down today’s barriers - cost, required knowledge of robotics and the efforts needed for different groups in society to explore and learn about robots. The Misty robot provides researchers, innovators and educators with an easy-to-use and creative tool to explore social robotics, ranging from quick and simplistic prototypes to advanced human-robot interactions. By leveraging the power of the social robotics community, Misty users can share their experiences and quickly gain traction in their development and research. Misty Robotics are creating new opportunities for the research and innovation industry to further understand how social robots will be useful in our society. Misty Robotics believes in the role and positive impact that robots will have in our lives, and is part of the early revolution together with researchers and innovators to define the future role of robots in society.
Investor
Mar 2017
Astronomer empowers data teams to bring mission-critical analytics, AI, and software to life and is the company behind Astro, the industry-leading DataOps platform powered by Apache Airflow®. Astro accelerates building reliable data products that unlock insights, unleash AI value, and powers data-driven applications. Trusted by more than 700 of the world’s leading enterprises, Astronomer lets businesses do more with their data. To learn more, visit www.astronomer.io Apache® and Apache Airflow® are either registered trademarks or trademarks of the Apache Software Foundation in the United States and/or other countries. No endorsement by the Apache Software Foundation is implied by the use of these marks. All other trademarks are the property of their respective owners.
Board Member & Venture Investor
Sep 2014
Follow us today to keep up to date on company news and product updates! Myriad Neuroscience is a personalized medicine company that specializes in helping physicians determine the right medication for individual patients who have Behavioral Health disorders. The GeneSight analysis is based on pharmacogenomics, the study of the genetic factors that influence an individuals response to drug treatments. For more information, please visit: www.genesight.com
Board Member & Venture Investor
Sep 2014
NuMedii discovers and de-risks effective new drugs by translating Life Sciences Big Data into therapies with a higher probability of therapeutic success. The Company’s proprietary and dynamic Big Data technology, developed in Atul Butte’s lab at Stanford University and licensed exclusively to NuMedii, consists of hundreds of millions of human, biological, pharmacological and clinical data points that the company has normalized and annotated. The company integrates these data with proprietary network-based algorithms to find both drug candidates and biomarkers predictive of efficacy for diseases.
late stageBiotechnology
Investor
Sep 2014
NuMedii discovers and de-risks effective new drugs by translating Life Sciences Big Data into therapies with a higher probability of therapeutic success. The Company’s proprietary and dynamic Big Data technology, developed in Atul Butte’s lab at Stanford University and licensed exclusively to NuMedii, consists of hundreds of millions of human, biological, pharmacological and clinical data points that the company has normalized and annotated. The company integrates these data with proprietary network-based algorithms to find both drug candidates and biomarkers predictive of efficacy for diseases.
late stageBiotechnology
Investor
Sep 2014
Follow us today to keep up to date on company news and product updates! Myriad Neuroscience is a personalized medicine company that specializes in helping physicians determine the right medication for individual patients who have Behavioral Health disorders. The GeneSight analysis is based on pharmacogenomics, the study of the genetic factors that influence an individuals response to drug treatments. For more information, please visit: www.genesight.com
Investor
Jun 2014
DNAnexus combines expertise in cloud computing and bioinformatics to create the global network for genomic medicine. DNAnexus provides security, scalability, and collaboration for enterprises and organizations that are pursuing genomic-based approaches to health in order to accelerate medical discovery. DNAnexus is supporting customers around the world that are tackling some of the most challenging and exciting opportunities in human health.For more information, please visit: https://dnanexus.com and follow us at @DNAnexus.
Board Observer & Venture Investor
Jun 2014
DNAnexus combines expertise in cloud computing and bioinformatics to create the global network for genomic medicine. DNAnexus provides security, scalability, and collaboration for enterprises and organizations that are pursuing genomic-based approaches to health in order to accelerate medical discovery. DNAnexus is supporting customers around the world that are tackling some of the most challenging and exciting opportunities in human health.For more information, please visit: https://dnanexus.com and follow us at @DNAnexus.
Board Member
Sep 2011
CareMessage is the largest patient engagement platform for underserved populations in the United States. We envision a world where all people regardless of income or background achieve equitable health outcomes. We power the care for more than 7 million underserved patients at over 300 safety net organizations nationwide who receive timely healthcare information, preventive care reminders, appointment reminders, local resources, and health coaching through interactive voice and text messaging. Founded in 2012 at Stanford University, CareMessage has raised over $25 million from Google.org, William K. Bowes Jr. Foundation, Pershing Square Foundation, Y Combinator, Schmidt Futures, and others to leverage technology to help safety net organizations fulfill the essential needs of underserved populations
Show all 18 investments ↓
Experience · 26 entries
All (26)
Investments (19)
Founder (2)
Board (5)
2023
Investor
Apr 2023
Tembo is the Postgres developer platform for building every data service. Our mission is to collapse the database sprawl of the modern data stack with a unified developer platform. With Tembo, developers can quickly create and deploy specialized data services using Stacks, pre-built Postgres configurations, and deployments without complex builds or additional data teams.
2021
Investor
Apr 2021
Using microbes to drug the undruggable
2019
Investor
Sep 2019
At Enveda, we are systematically translating molecules found in medicinal plants into new drugs for challenging diseases. Our platform harnesses natures complexity with the help of cutting-edge advancements in knowledge graphs, machine learning, and metabolomics.
Investor
Mar 2019
Endpoint Health is a Precision-First therapeutics company dedicated to addressing unmet needs in immune-mediated chronic and acute diseases. We leverage our proprietary artificial intelligence (AI) platform and combine companion diagnostics with therapeutics to develop precision therapies. Our vision is a world in which all patients get the best treatment possible for their unique biology and disease.
2018
Investor
Mar 2018
Engineering next generation kinase inhibitors with computation.
Show all 26 entries ↓
Investment activity
2004–2023 · 19 investments
20041200512010120112201462017220182201922021120231
Recent (last 2 years)Earlier