Roger Wyse

Founder & Managing Partner at Spruce Capital Partners

📍 San Francisco, California, United States🔄 Updated October 2026💼 8 investments📅 26 years investing🗓 Last invested Jan 2022
VC🌍 United States
8
Total investments
4
Early stage
1
Mid stage
1
Late stage
26y
Years active

Portfolio

6 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Board Observer
Jun 2021
Pivot Bio is one of the worlds leading innovative agtech companies, delivering farmers patented crop nutrition technologies.
Board Member
Jan 2017
Infinant Health, Inc is a privately held company committed to changing the trajectory of human health, one baby at a time, through our deep understanding of infant nutrition and the gut microbiome. Years of proprietary research into the role of human milk and its impact on human development led to our groundbreaking discovery of B. infantis EVC001, a natural bacterial strain foundational to infant immune health. Unfortunately, B. infantis had been almost completely eradicated from infants in developed countries due to unintended consequences of modern medicine such as feeding and birthing practices. Now, there is a way to change that. What we found is that EVC001, our specific strain of B. infantis, is essential in developing a healthy microbiome, reducing potential harmful bacteria that may be linked to prevalent childhood issues such as allergies and type 1 diabetes, moderating inflammation, and supporting healthy immune system function. We believe the greatest chance to impact future health begins early, right after birth—a once in a lifetime opportunity where rapid development and radical changes occur. By unlocking human nutrition's full potential through introducing beneficial bacteria during early infancy, we can help build a foundation for better health.
Member of the Board
Apr 2016
Inscripta® is a life science technology company committed to creating a cleaner, healthier, and more sustainable world through biomanufacturing. A global leader in genome engineering, our innovations are designed to unlock the full potential of the bioeconomy. We are committed to the continued development of critical technologies that enable scientists to bolster and expand domestic biomanufacturing, and spur new, safe, and secure biotech innovations. Inscripta supports customers around the world from facilities in Pleasanton and Burlingame, California. To learn more, visit Inscripta.com and follow @InscriptaInc.
Member of the Board
Apr 2016
Inscripta® is a life science technology company committed to creating a cleaner, healthier, and more sustainable world through biomanufacturing. A global leader in genome engineering, our innovations are designed to unlock the full potential of the bioeconomy. We are committed to the continued development of critical technologies that enable scientists to bolster and expand domestic biomanufacturing, and spur new, safe, and secure biotech innovations. Inscripta supports customers around the world from facilities in Pleasanton and Burlingame, California. To learn more, visit Inscripta.com and follow @InscriptaInc.
Founder & Board Member
Apr 2016
NAPIGEN is a biotechnology company that addresses novel genome engineering of various organisms such as plants, microbes and animals. Our technology targets two special cellular components known as organelles that harbor their own DNA. Those organelles are called mitochondria and chloroplasts. Both organelles are important to create energy for cells to grow. They are also critical for producing various biochemical molecules key to specific pathways and functions. Our genome technology has broad application areas. They range from industrial biotechnology to animal and human healthcare as well as to agriculture. Our mission is to harness the potentials of organelles to make our society a better place to live.
Board Member
2000
CropDesign is an agricultural biotech company delivering agronomic traits for the global commercial seed markets. The company's trait discovery and development program focuses on enhancing grain yield in crops such as corn and rice. Corn is the world's leading crop in terms of seed market value and yield enhancement is the most important value driver for both growers and seed companies. The rice seed market is today less developed but is expected to represent a substantial growth opportunity for the years to come.
Experience · 16 entries
All (16)
Investments (7)
Founder (3)
Board (7)
2022
Board Member
Jan 2022
The National Academy of Sciences (NAS) is an honorific society of distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare. The NAS was signed into being by President Abraham Lincoln on March 3, 1863, at the height of the Civil War. As mandated in its Act of Incorporation, the NAS has, since 1863, served to "investigate, examine, experiment, and report upon any subject of science or art"​ whenever called upon to do so by any department of the government. Scientific issues would become even more contentious and complex in the years following the war. To keep pace with the growing roles that science and technology would play in public life, the institution that was founded in 1863 eventually expanded to include the National Research Council in 1916, the National Academy of Engineering in 1964, and the National Academy of Medicine (formerly known as the Institute of Medicine) in 1970. Collectively, the four organizations are known as the National Academies of Sciences, Engineering, and Medicine.
2021
Board Observer
Jun 2021
Pivot Bio is one of the worlds leading innovative agtech companies, delivering farmers patented crop nutrition technologies.
2017
Board Member
Jan 2017
Infinant Health, Inc is a privately held company committed to changing the trajectory of human health, one baby at a time, through our deep understanding of infant nutrition and the gut microbiome. Years of proprietary research into the role of human milk and its impact on human development led to our groundbreaking discovery of B. infantis EVC001, a natural bacterial strain foundational to infant immune health. Unfortunately, B. infantis had been almost completely eradicated from infants in developed countries due to unintended consequences of modern medicine such as feeding and birthing practices. Now, there is a way to change that. What we found is that EVC001, our specific strain of B. infantis, is essential in developing a healthy microbiome, reducing potential harmful bacteria that may be linked to prevalent childhood issues such as allergies and type 1 diabetes, moderating inflammation, and supporting healthy immune system function. We believe the greatest chance to impact future health begins early, right after birth—a once in a lifetime opportunity where rapid development and radical changes occur. By unlocking human nutrition's full potential through introducing beneficial bacteria during early infancy, we can help build a foundation for better health.
2016
Member of the Board
Apr 2016
Inscripta® is a life science technology company committed to creating a cleaner, healthier, and more sustainable world through biomanufacturing. A global leader in genome engineering, our innovations are designed to unlock the full potential of the bioeconomy. We are committed to the continued development of critical technologies that enable scientists to bolster and expand domestic biomanufacturing, and spur new, safe, and secure biotech innovations. Inscripta supports customers around the world from facilities in Pleasanton and Burlingame, California. To learn more, visit Inscripta.com and follow @InscriptaInc.
Member of the Board
Apr 2016
Inscripta® is a life science technology company committed to creating a cleaner, healthier, and more sustainable world through biomanufacturing. A global leader in genome engineering, our innovations are designed to unlock the full potential of the bioeconomy. We are committed to the continued development of critical technologies that enable scientists to bolster and expand domestic biomanufacturing, and spur new, safe, and secure biotech innovations. Inscripta supports customers around the world from facilities in Pleasanton and Burlingame, California. To learn more, visit Inscripta.com and follow @InscriptaInc.
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Investment activity
2000–2022 · 8 investments
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