Matthew Sutton

Investor | Academic | Harvard Business School

📍 Cambridge, Massachusetts, United States🔄 Updated October 2026💼 55 investments📅 19 years investing🗓 Last invested Sep 2026
VC🌍 United States50+ investmentsInvested this quarter
55
Total investments
27
Early stage
3
Mid stage
1
Late stage
19y
Years active

Portfolio

53 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Investor
Sep 2026
Cosmic Robotics builds Physical AI for the construction industry, with a focus on robots that build solar farms and data centers today.
Investor
Sep 2026
Hardware for AI and AI for hardware. We design and sell chips for on-edge AI inference. Ultra-low power and ultra-fast.
Investor | Advisor
Aug 2026
Dyle is an agentic platform that identifies churn risk and expansion opportunities, helping teams grow revenue and prove ROI across every account.
Investor
Aug 2026
We’re pioneering advancements in AI hardware and software, building foundational technology that makes intelligence ambient, personal, and ever present.
Investor
Jul 2026
Aranya converts bare metal GPU infrastructure into highly custom production clusters in under 48 hours, bridging the gap between what data centers offer and what AI workloads really need.
Investor
Jul 2026
Silicon Data is on a mission to revolutionize compute markets through unparalleled data transparency. As pioneers in the field, Silicon Data is dedicated to developing cutting-edge products that provide essential intelligence and efficiency to compute markets worldwide.
Investor
Jul 2026
Ploy turns your website into your hardest-working employee — an AI growth teammate that builds, optimizes, and publishes high-converting marketing sites.
Investor
Jun 2026
Cignara is building AI voice + chat agents for automating customer support at large B2C enterprises. We work with F500 companies across retail, banking, travel and telecom to handle use cases such as appointment scheduling, handling sales inquiries, customer ticket resolution, outbound dispatch coordination, etc.
Investor
Jun 2026
Lumos Health builds AI that predicts how drugs affect multiple organ systems simultaneously — cardiac, renal, hepatic, respiratory, metabolic — from continuous physiological data. Every Phase I clinical trial monitors safety with disconnected, single-timepoint measurements analyzed weeks later. Lumos processes the same data your trial already collects — continuous ECG waveforms, vital signs, lab results, drug administration records — and predicts multi-organ drug effects in real time. Cross-organ interactions that single-endpoint monitoring misses become visible hours to days earlier. Our foundation model was trained on 42,000+ ICU patients and 200+ drugs. It learned how human physiology responds to pharmacological intervention by ingesting continuous waveforms fused with clinical data. In validation, the model discovered known drug-organ interactions — nephrotoxicity, respiratory depression, cardiac perturbation — in a fully unsupervised setting. No labels. No prior pharmacological knowledge. Just physiological signal. Built for the drugs that need it most: novel mechanisms with no historical safety database. RNA therapeutics. Gene therapies. Combination regimens. If there is no reference compound to benchmark against, Lumos provides the computational safety baseline. Founded by a Princeton mathematician, backed by pharma and healthcare investors, and advised by clinicians from Penn Medicine, Princeton, and Harvard. We are accepting early access partners for Phase I safety monitoring. Contact: zach@projectlumos.org
Pre-Seed Investor
Jan 2026
Diffraqtion is a Somerville, MA, space startup building the world’s first quantum camera powering the largest ultra-high-resolution imaging satellite network. Combining quantum photonics and AI, Diffraqtion enables machines to see further and think faster, advancing space exploration, defense, and intelligent systems worldwide.
Seed Investor
Jan 2026
A network for entrepreneurs building in stealth. Submit your information here so investors can find you: harmonic.ai/get-discovered
Seed Investor
Nov 2025
Re-imagining the marketing function in an AI-native era, automate your content marketing Y Combinator, Pelion Venture, Blast Club, Transpose Platform, Progressive Venture, Wefunder (Capitalized Fund), Mindworks Capital, and more
Seed Investor
Nov 2025
Dome provides the developer infrastructure to access, analyze, and build on prediction markets. With our unified API, developers can access live and historical data, including granular datasets not available through native APIs, which allows them to backtest strategies and power their trading applications. We make it simple to build bots, embed prediction market data into products, and deploy strategies across multiple platforms through one interface.
Show all 53 investments ↓
Experience · 62 entries
All (62)
Investments (53)
Founder (4)
2026
Investor
Sep 2026
Cosmic Robotics builds Physical AI for the construction industry, with a focus on robots that build solar farms and data centers today.
Investor
Sep 2026
Hardware for AI and AI for hardware. We design and sell chips for on-edge AI inference. Ultra-low power and ultra-fast.
Investor | Advisor
Aug 2026
Dyle is an agentic platform that identifies churn risk and expansion opportunities, helping teams grow revenue and prove ROI across every account.
Investor
Aug 2026
We’re pioneering advancements in AI hardware and software, building foundational technology that makes intelligence ambient, personal, and ever present.
Show all 62 entries ↓
Investment activity
2007–2026 · 55 investments
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