Tom Medrek

Entrepreneur, Angel Investor and Startup Advisor & Mentor

📍 Greater Boston, United States🔄 Updated September 2026💼 26 investments📅 8 years investing🗓 Last invested Nov 2025
VC🌍 United States20+ investmentsInvested this year
26
Total investments
7
Early stage
10
Mid stage
1
Late stage
8y
Years active

Portfolio

25 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Seed Investor
Nov 2025
We are making a simple blood test to differentiate and quantify nearly all pathogen genes in hospitalized patients. Pathogen DNA is detectable at early stages of infection, and by quantifying it over time, we aim to change how infections are managed at every phase of care. The solution is “hidden in plain sight.” We enhance digital PCR hardware that hospitals are already starting to adopt with machine learning and programmable chemistry. Today, PCR tests have become routine but only for limited sets of pathogens. By making PCR both comprehensive and extremely sensitive, we will detect the range of pathogen genes at the "helix in the haystack" levels found in blood.
Seed Investor
Oct 2025
Kano Therapeutics is a biotech startup enabling safe, effective, and flexible correction of gene-length stretches of DNA through a new class of biomaterials: circular single-stranded DNA. By building a “one stop shop” product development platform for single-stranded DNA templates that combines manufacturing, application, and computational tools we bridge the gap between editing genes and totally replacing them.
Pre-Seed Investor
Sep 2025
Accelerating Genetic Disease Diagnosis via Education and Testing.
Pre-Seed Investor
Jun 2025
ClearCut Surgical was created by surgeons for surgeons to solve a universally frustrating operating room problem: how to manage fluid buildup during tissue electrocautery. Through surgeon-driven innovation, ClearCut has developed a novel electrocautery surgical tool with continuous smoke evacuation and on-demand fluid suction.
Seed Investor
Jun 2024
Surgicure Technologies, Inc., is a medical device company committed to improving patient care through innovative solutions. We specialize in airway management for both civilian and military applications, enabling healthcare professionals to reduce adverse events by providing devices that optimize patient breathing, improve deployment speed, and contribute to improved safety and quality of care.
Seed Investor
May 2024
No booth, no time, no problem. Occupational hearing testing and hearing protector fit testing are easy and efficient with the WAHTS headset and audhere app. WAHTS is an OSHA- and ANSI-compliant calibrated headset with a built-in wireless audiometer. The WAHTS earcups attenuate sound on par with a single-walled sound booth. Pairing with the audhere app makes it easy to manage automated testing of groups or conduct one-on-one testing for individual needs. The system can be used in conference rooms, waiting areas, classrooms, occupational exam rooms, and more!
Seed Investor
Sep 2023
VALIS builds AI-powered software that makes recycling more profitable, material supply chains more sustainable, and closes the loop on a circular economy for metal fabrication.
Seed Investor
Sep 2023
myBiometry is a platform to remotely monitor and manage patients with chronic conditions using software and biomarker data generated from proprietary sensors. Our initial focus is asthma.
Seed Investor
May 2023
TETmedical, Inc. (Tethered Enzyme Technologies) is a clinical stage platform nanomedicine company focused on in vitro diagnostics that enable insights for high-consequence disease decision making. TET emerged out of groundbreaking innovations originating at Cornell University. Our device measures less than a hundredth the width of a human hair. It is a miniature, functioning, highly stable molecular machine, capable of performing chemical operations with high sensitivity, stability, and speed (thousands of times faster than antibody assays): a patented “TET nanobot”, consisting of thousands of enzymes tethered to a silica nanoparticle. TETmedical’s first product is the NSE-FAST (Neuron Specific Enolase Functional Activity Stroke Test), the first in-vitro diagnostic for brain injury from stroke.
Seed Investor
Apr 2023
florrent is a Massachusetts-based, minority-owned DeepTech company innovating to design and build the next generation of high energy density ultracapacitors that will stabilize electrical grids and address critical bottlenecks for the adoption of renewable energies, electric vehicles, and net-zero buildings. Our ultracapacitors are manufactured in Western Massachusetts from abundant and regenerative hemp biomass, grown domestically in the US by Black and Indigenous farmers.
Seed Investor
Jan 2023
Xcelerium is a fabless semiconductor company that develops high-performance domain specific processors for converged workloads at the edge of the network involving wireless communications, advanced radar, image signal processing, computer vision and ML/AI. Xcelerium was established in 2020 by an experienced team from Qualcomm, Broadcom and Intel with more than 25 years of experience developing high-volume products.
Seed Investor
Jan 2022
RevenueBase specializes in delivering targeted and relevant B2B data, empowering sales and marketing teams to scale their programs effortlessly and hit their revenue numbers. With market-specific databases, transparent pricing, and unparalleled customer support, were the go-to data partner for leading B2B companies.
Pre-Seed Investor
May 2021
AOA Dx is leading a revolutionary breakthrough in early-stage cancer detection, leveraging the transformative potential of AI and our proprietary biomarker technology. At the heart of this innovation is our GlycoLocate platform, a multi-omics approach powered by lipids, metabolites and proteins. This platform is setting a new gold standard in the quest for life-saving early cancer diagnostics. We are now advancing AKRIVIS GD™, a cutting-edge liquid biopsy test designed specifically for the early detection of ovarian cancer.
Investor
Apr 2021
Our workforce development mission is to create a world in which all people, regardless of economic status, can benefit from education and employment opportunities to reach their peak potential. CDFI.
Board Observer, Advisor, Investor
Mar 2021
VesprSolar is a solar hardware company focused on making PV solar installation faster, cheaper, and more reliable.
Show all 25 investments ↓
Experience · 27 entries
All (27)
Investments (26)
Founder (1)
Board (1)
2025
Seed Investor
Nov 2025
We are making a simple blood test to differentiate and quantify nearly all pathogen genes in hospitalized patients. Pathogen DNA is detectable at early stages of infection, and by quantifying it over time, we aim to change how infections are managed at every phase of care. The solution is “hidden in plain sight.” We enhance digital PCR hardware that hospitals are already starting to adopt with machine learning and programmable chemistry. Today, PCR tests have become routine but only for limited sets of pathogens. By making PCR both comprehensive and extremely sensitive, we will detect the range of pathogen genes at the "helix in the haystack" levels found in blood.
Seed Investor
Oct 2025
Kano Therapeutics is a biotech startup enabling safe, effective, and flexible correction of gene-length stretches of DNA through a new class of biomaterials: circular single-stranded DNA. By building a “one stop shop” product development platform for single-stranded DNA templates that combines manufacturing, application, and computational tools we bridge the gap between editing genes and totally replacing them.
Pre-Seed Investor
Sep 2025
Accelerating Genetic Disease Diagnosis via Education and Testing.
Pre-Seed Investor
Jun 2025
ClearCut Surgical was created by surgeons for surgeons to solve a universally frustrating operating room problem: how to manage fluid buildup during tissue electrocautery. Through surgeon-driven innovation, ClearCut has developed a novel electrocautery surgical tool with continuous smoke evacuation and on-demand fluid suction.
2024
Seed Investor
Jun 2024
Surgicure Technologies, Inc., is a medical device company committed to improving patient care through innovative solutions. We specialize in airway management for both civilian and military applications, enabling healthcare professionals to reduce adverse events by providing devices that optimize patient breathing, improve deployment speed, and contribute to improved safety and quality of care.
Show all 27 entries ↓
Investment activity
2018–2025 · 26 investments
2018220193202052021420221202352024220254
Recent (last 2 years)Earlier