Stephen Bruso

Digital Health VC

📍 Cambridge, Massachusetts, United States🔄 Updated September 2026💼 24 investments📅 6 years investing🗓 Last invested Sep 2025
VC🌍 United States20+ investmentsInvested this year
24
Total investments
4
Early stage
5
Mid stage
7
Late stage
6y
Years active

Portfolio

21 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Board Member
Sep 2025
AdaptX empowers clinical leaders to manage variation in care across workflows and treatments. Self-serve, on-the-fly. To explore AdaptX’s real-world results across environments of care, visit adaptx.com/case-studies.
Board Member
Jan 2024
Casana is innovating healthcare delivery with a smart toilet seat that enables effortless, integrated, and consistent in-home health monitoring. The FDA-cleared Heart Seat® captures heart rate and blood oxygenation. The healthcare system has been searching for this actionable intelligence for decades, and it turns out, we were sitting on a great idea all along. The Heart Seat will become commercially available upon future clearance of non-invasive blood pressure.
Board Observer
Aug 2023
FlyteHealth is a tech-enabled healthcare services organization born of the belief that everyone deserves to live a healthy life. Our efforts to bring the most effective health care to people with obesity, while making it cost-efficient to do so, mean that more people can transform their health for the better—now and for the rest of their lives. We were founded by physicians who were the first to recognize obesity not as a simple issue of willpower, but as a complex disease that requires expert medical treatment. Based on their decades of research and caring for patients, our clinically proven approach combines the latest in personalized medication therapy and behavior coaching that not only helps people lose weight for the long term, but significantly improves related conditions. Our obesity treatment platform, powered by Flyte Intelligence, is built from the largest data set of obesity and chronic disease research available, empowering healthcare providers—our own FlyteHealth clinicians and those of our healthcare partners—to deliver the highest standards of care, consistently. While others are jumping on the GLP-1 bandwagon, we see a better way. One that allows employers and payers to offer the best in obesity care, while keeping costs under control. FlyteHealth clinicians prescribe GLP-1 medications strategically, alongside lower-cost generics, for treatment that’s specific to what our patients’ bodies truly need and delivers better control over health care costs. Obesity care goes well beyond weight loss. FlyteHealth gives patients the power to achieve a lifetime of better health. Whether they are actively losing weight or maintaining a normal BMI, we deliver clinical care and coordinate with care teams to help them manage optimal health for life. At FlyteHealth, we’re committed to making sure nothing stands in the way of someone getting the care they need. Together, we’re a collective force for fighting chronic disease.
Board Member
Apr 2023
A team of pediatricians in your pocket! 👩🏽‍⚕️👨🏼‍⚕️🧑🏻‍⚕️ ⌚️ Save time 💵 Save money 🩺 Great care 👇 Learn more
Board Member
Apr 2023
Every 4.5 minutes, a baby is born with a birth defect in the United States. Unfortunately, many of these defects go undetected during prenatal scans, at a time when they are still easily treatable. This is caused by limited access to maternal care, the complexity of the defects, and the range of accuracy produced by the subjective interpretation of ultrasound imaging. Furthermore, this issue is exacerbated by a global shortage of maternal healthcare providers, particularly in rural areas. We are on a mission to solve that by advancing and democratizing the highest standard of prenatal ultrasounds through our proprietary AI. Our technology harnesses the power of AI to support a broad spectrum of healthcare providers in rural and urban communities, allowing them to practice at the top of their licenses. With AI in the imaging workflow, clinicians can more confidently deliver timely interventions, enhance pregnancy outcomes, identify high-risk pregnancies to reduce maternal mortality, and significantly lower infant mortality rates.
Board Member
Aug 2022
Our mission is to promote the wellbeing of people of all ages through our innovative and empowering digital solutions. By teaming up with schools, colleges, and workplaces, we strive to cultivate positive mindsets and create thriving communities. Our vision is a future where everyone has the psychological tools to bounce back from adversity, connect meaningfully to others, and pursue their passions—a world where all individuals and organisations can flourish with purpose.
Board Member
Jun 2022
As a pioneer in telemedicine for Skilled Nursing Facilities, we are committed to revolutionizing senior care by breaking down barriers and delivering exceptional healthcare without limitations. Established in 2020, our groundbreaking platform has achieved a remarkable 50%+ reduction in patient transfers from Skilled Nursing Facilities (SNFs) to Emergency Departments. At Curve Health, we seamlessly integrate telemedicine, electronic health data, predictive analytics, and billing into one unified platform. This comprehensive approach ensures higher quality care, substantial return on investment, and an unparalleled patient experience. To discover more about our innovative solutions, visit us at: https://www.curvehealth.com/
Board Member
May 2022
At Koa Health, we’ve made it our mission to leverage technology and research to create simple, personal, and accessible mental health support by combining evidence, cutting-edge tech, and user-centered design. We create breakthrough interventions backed by science with one clear goal: to improve people’s mental health. Designed to help your employees find the right mental healthcare at the right time, Koa Health’s comprehensive care model, Koa Care 360 offers employees simple navigation and personalized, evidence-based care built with the world’s leading clinician-academics. Koa Health provides an integrated approach to care that delivers mental health for everyone, whether they prefer digital-first care or would benefit from clinical services delivered by a human. Available to more than 3 million users worldwide, Koa Health addresses the full continuum of mental health needs – from prevention to treatment. Backed by leading investors such as Morningside, Ancora Finance Group, Wellington Partners Life Sciences, and MTIP, Koa Health leverages deep clinical expertise, research, and technology to deliver effective and accessible care that adapts to users’ unique circumstances, leading to lasting behavior change and positive health outcomes across the full continuum of mental health. Want to learn more about life at Koa Health? Visit our website at koahealth.com Our international team of behavioral scientists, developers, designers and health innovation leaders work, learn and grow together in a collaborative and inclusive culture. Want to learn more about life at Koa Health? Visit our website at koahealth.com
Board Member
May 2022
SimpliFed is democratizing access to baby feeding and breastfeeding services by providing high-quality virtual care that is covered by insurance. The Ithaca, New York-based company envisions a world where every parent feels good about feeding their family – because baby feeding and breastfeeding is central to maternal and infant health. Founded in 2019 by Andrea Ippolito, a biomedical engineer and mom of two, SimpliFed provides evidence-based and inclusive virtual baby feeding services to everyone, no matter how they choose to feed their baby. Simplifed’s mission is to create a new model for optimal baby feeding by building trusted relationships with parents, partnering with healthcare payers and providers, and shifting policy, practice, and narratives to drive health and economic equity, starting with baby’s first foods. For more information on SimpliFed: https://www.simplifed.com/
Board Member
Oct 2021
At ieso, AI is in our DNA. We began using AI over a decade ago to decode patterns in mental health and improve therapy with our NHS partners in the UK. Now, we’ve brought our expertise to the U.S. with Velora, our generative AI-powered software that supports people with symptoms of anxiety and depression. Developed by our expert clinical and AI teams, Velora integrates seamlessly via API or white-lable web app into clinical workflows and care platforms to deliver safe, personalized care that works. Velora is: 🔹 Built on over 750,000 hours of human-delivered therapy, not a generic LLM. 🔹 Clinically guided and human-reviewed, not a black box. 🔹 Proven to deliver outcomes on par with human-delivered care. 🔹 Ready to deploy, allowing digital health companies to offer immediate access to mental health support, at a fraction of traditional costs. Our groundbreaking research has been published in JMIR, JAMA Psychiatry, Nature Mental Health, and Psychological Medicine and featured by TechCrunch, The New Yorker, TED, and MIT Technology Review. In 2024, Newsweek recognized us as one of the World’s Best Digital Health Companies. 🔗 Learn more: www.ieso.ai 📖 Read our latest preprint: https://osf.io/preprints/psyarxiv/8kvm6_v1 📖 Read our peer-reviewed research in JMIR: https://www.jmir.org/2025/1/e69351
Board Member
Oct 2021
Wellinks is the COPD disease management company providing individuals with the personalized care and support necessary for successful self-management. We prioritize the unique needs of each member to establish a clear path to better health. Our programs extend the reach of existing care resources, and fill gaps where they are absent. Respiratory specialists and our health coaches work one-on-one and across a community of members to personalize the experience and unlock the power of the individual in their journey to better health. Our care pathways are supported by a suite of innovative and simple to use technology, including a kit of connected devices and the Wellinks app, bridging the gap between doctor visits and allow patients to manage their COPD from wherever life takes them. Wellinks provides a welcoming and inclusive environment where members trust they will receive the best possible care and guidance in managing their COPD. Our solution is intuitive, engaging, and fully integrated across the care journey — empowering patients with the peace of mind and freedom to live fully and breathe freely.
Board Member
Sep 2021
Having experienced first-hand the toll of sleep deprivation and the lack of tailored and accessible help for parents, we set out to solve this problem in a new way with a team of sleep experts and data scientists. Huckleberry's first product gets kids from newborns to 5 years old sleeping better and longer. After understanding your child's sleep scenario, our algorithms and sleep experts determine what will work for your situation. Possible to achieve this without leaving your child to cry or medicating them? Yes indeed. Get started at: iOS: https://itunes.apple.com/us/app/huckleberry-sleep-improvement-for-families/id1169136078 Android: https://play.google.com/store/apps/details?id=com.huckleberry_labs.app Learn more at www.huckleberrycare.com.
Board Member
Jul 2021
MedRhythms is developing next-generation neurotherapeutics that leverage the power of music and technology to redefine whats possible in brain health, for patients around the world. Our devices are designed to improve walking, mobility and related functional outcomes via a proprietary, patented technology platform. This platform combines sensors, software, and music with advanced neuroscience to target neural circuitry. We are developing a pipeline of digital therapeutics across a range of neurological conditions, including stroke, multiple sclerosis and Parkinson’s disease. For more information about how we are pioneering digital therapeutics, visit https://medrhythms.com/
Board Member
Jun 2021
DeepCure discovers transformative small molecule therapies for immune and inflammatory diseases. The company uses a chemistry platform that combines AI, physics-based tools and automated chemical synthesis to identify truly novel molecules that address unsolved challenges in drug discovery. The pipeline includes an oral STAT6 program with multiple novel scaffolds and an oral BRD4(BD2) program with the first truly selective inhibitor. DeepCure expects to start in clinical trials in 2025.
Board Member
Jan 2021
Innodem Neurosciences is committed to improving the effectiveness and quality of life and care of patients with neurological problems. Innodem works with the pharmaceutical industry, leading medical professionals, and artificial intelligence experts to develop and promote Eye Movement Biomarkers (EMBs) & Gaze Mapping Biomarkers (GMBs) as important clinical assessment tools in the field of neurology. It is building a series of disease-specific tests embodied in an intuitive App that captures EMB & GMB data. The vision is that over time, while leveraging the latest advances in machine and deep learning, this EMB/GMB platform will assist users to accurately diagnose and monitor neurological disorders affecting eye-movements or cognition such as multiple sclerosis, Alzheirmer’s, Parkinson’s or related disorders, Frontotemporal dementia, Cancer-related cognitive impairment (Chemo Brain) and many others.
Show all 21 investments ↓
Experience · 27 entries
All (27)
Investments (24)
Board (24)
2025
Board Member
Sep 2025
AdaptX empowers clinical leaders to manage variation in care across workflows and treatments. Self-serve, on-the-fly. To explore AdaptX’s real-world results across environments of care, visit adaptx.com/case-studies.
2024
Board Member
Apr 2024
Freespira® is an FDA-cleared at-home treatment proven to significantly reduce or eliminate Panic Disorder and PTSD symptoms by training users to normalize respiratory irregularities in just 28 days. Health plans, self-insured employers and the Veteran’s Administration use the company’s drug-free solution to improve quality of life, reduce medical spending and support the appropriate use of valuable healthcare resources. Find out how at www.freespira.com
Board Member
Jan 2024
Casana is innovating healthcare delivery with a smart toilet seat that enables effortless, integrated, and consistent in-home health monitoring. The FDA-cleared Heart Seat® captures heart rate and blood oxygenation. The healthcare system has been searching for this actionable intelligence for decades, and it turns out, we were sitting on a great idea all along. The Heart Seat will become commercially available upon future clearance of non-invasive blood pressure.
2023
Board Observer
Aug 2023
FlyteHealth is a tech-enabled healthcare services organization born of the belief that everyone deserves to live a healthy life. Our efforts to bring the most effective health care to people with obesity, while making it cost-efficient to do so, mean that more people can transform their health for the better—now and for the rest of their lives. We were founded by physicians who were the first to recognize obesity not as a simple issue of willpower, but as a complex disease that requires expert medical treatment. Based on their decades of research and caring for patients, our clinically proven approach combines the latest in personalized medication therapy and behavior coaching that not only helps people lose weight for the long term, but significantly improves related conditions. Our obesity treatment platform, powered by Flyte Intelligence, is built from the largest data set of obesity and chronic disease research available, empowering healthcare providers—our own FlyteHealth clinicians and those of our healthcare partners—to deliver the highest standards of care, consistently. While others are jumping on the GLP-1 bandwagon, we see a better way. One that allows employers and payers to offer the best in obesity care, while keeping costs under control. FlyteHealth clinicians prescribe GLP-1 medications strategically, alongside lower-cost generics, for treatment that’s specific to what our patients’ bodies truly need and delivers better control over health care costs. Obesity care goes well beyond weight loss. FlyteHealth gives patients the power to achieve a lifetime of better health. Whether they are actively losing weight or maintaining a normal BMI, we deliver clinical care and coordinate with care teams to help them manage optimal health for life. At FlyteHealth, we’re committed to making sure nothing stands in the way of someone getting the care they need. Together, we’re a collective force for fighting chronic disease.
Board Member
Apr 2023
A team of pediatricians in your pocket! 👩🏽‍⚕️👨🏼‍⚕️🧑🏻‍⚕️ ⌚️ Save time 💵 Save money 🩺 Great care 👇 Learn more
Show all 27 entries ↓
Investment activity
2020–2025 · 24 investments
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