Sri R.

Open Culture Science builds Habitat™, the personal computer of cell culture, an AI-native hardware platform that automates the growth and analysis of human cell and tissue models. Each desktop-sized system combines microfluidic culture, high-density electrophysiology, and live imaging into a single instrument designed from the ground up to be operated by AI agents rather than pipettes, closing the loop from experimental design to execution to interpretation without a human at every step. Biology has less than 1% of the data needed to model the living cell, and what exists is sparse and under-documented. The bottleneck is no longer reasoning; its the ability to run dense, reproducible experiments on living tissue at scale. Habitat generates that data, and turns it into decisions in real time, on the same sample, across electrical, chemical, and optical axes. The architecture is centralized intelligence with decentralized execution. Every attempt to consolidate the wet lab into one mega-facility has failed because all the specimens, expertise, and instruments cant be co-located. We put a programmable, auditable lab wherever the science is. As the FDA accelerates the shift toward human-relevant, reproducible, traceable data over animal models, Habitat delivers the infrastructure for that era, making biology as shareable, reliable, and collaborative as software.

Extellis is a satellite imaging company dedicated to delivering reliable Earth observations at an industrial scale. Our patented antennas, invented at Duke with DARPA-sponsored research, enable satellites that can take thousands of synthetic aperture radar (SAR) images per day. Blending wide-area scanning with high-volume captures brings advanced spaceborne monitoring capabilities with sensible economics to drive widespread adoption.

We combine event-driven distributed architecture with knowledge agents to perform real-time adaptive entity mapping that builds the blueprint for how an organizations knowledge is structured. This blueprint can be accessed by other classes of agents and by humans for entity and relationship resolution across many data and information workflows.

Our Al engine gives your developers the tools to create intelligent agents and workflows that run seamlessly on any hardware- from mobile phones to desktop systems. By enabling local inference for Al Agents, OpenInfer ensures data privacy, significantly reduces costs, and delivers always-available, long-chain reasoning. Unlock the full potential of smart devices everywhere, from robotics to next-generation personal assistants.

TieSet is the AI orchestration company behind STADLE, empowering enterprises to simplify and accelerate AI model development, deployment, and updates. Trusted by leading industries including insurance, manufacturing, and healthcare, STADLE reduces costs by up to 90%, improves accuracy by 40%, and speeds up model updates by 10x. Headquartered in Silicon Valley, TieSet is dedicated to making advanced AI accessible and efficient for businesses worldwide. Discover more at www.tieset.com.

Besxar is pioneering a new class of space-based manufacturing to overcome the limits of terrestrial semiconductor fabrication. The company builds reusable “Fabships” that harness the ultra-high vacuum (UHV) of space to produce ultra-pure substrates and precursor materials—essential building blocks for next-generation technologies. Manufacturing in space allows purity and yield levels impossible on Earth, effectively doubling chip cost-effectiveness for these critical applications. Traditional chip factories face constraints in power, cooling, and materials. Besxar’s autonomous orbital manufacturing platforms overcome these barriers and return to Earth after each mission—not only delivering materials but also capturing insights to refine performance. Each cycle improves precision, efficiency, and reliability, making every subsequent orbital manufacturing run more effective. Besxar’s materials serve industries that demand the highest-performance semiconductors, from AI and quantum computing to nuclear technologies and defense applications. By combining space-based production with a focus on domestic resilience, Besxar is rebuilding the U.S. semiconductor base and redefining how—and where—humanity’s most critical technologies are made.

Started by Stanford/MIT serial entrepreneurs, Ruby Robotics is working to maximize patient outcomes with tissue insights at the point of care. Using custom-built hardware and AI, our platform is being developed with the goals of optimizing biopsy and surgical procedure workflow while delivering disease analytics early in the patient’s journey. Ruby Robotics was acquired in 2025 by Intuitive Surgical.

Attimis is building distributed SaaS services utilizing Artificial Intelligence and Machine Learning to democratize, simplify, and secure cloud storage with three products. We lower the cost of egress, simplify multi-cloud configuration, and encourage movement of data.

SirenOpt is accelerating sustainable and smart manufacturing of advanced materials by delivering a manufacturing intelligence platform that uses intelligent characterization and real-time decision-making to drive the creation of innovative, high-performance products that fuel the advancement of society. SirenOpt is pioneering a paradigm shift in materials manufacturing intelligence by leveraging cold atmospheric plasma, machine learning and predictive analytics to non-destructively create a uniquely distinctive, multifaceted material fingerprint in real-time. SirenOpt transforms measurement blind spots into rich multi-layered material insights, which enable intelligent performance-centric decision-making. SirenOpt thus accelerates R&D and process optimization, enhances product performance, and delivers higher production quality to maximize value in both in-line and off-line applications. SirenOpt’s manufacturing intelligence platform has demonstrated use cases across battery, aerospace, semiconductor, electronic and many other advanced manufacturing segments in both inline production and offline tool deployments. SirenOpt was founded in 2022 as a spin-out from the UC Berkeley Chemical Engineering Department. SirenOpt is supported by the UC Berkeley Skydeck, Lawrence Berkeley National Laboratory Cyclotron Road and Activate science-driven startup accelerator programs.

NuMind allows software engineers, data scientists and non-experts alike to easily create state-of-the-art machine learning models powered by LLMs to process text automatically. Such models can be used for content moderation, email routing, news analysis, and any other task requiring text understanding. Thanks to our Interactive AI Development technology, NuMind allows to develop these custom models significantly faster than traditional solutions, and without compromise on performance. This tool is meant to be used by both machine learning experts and non-experts. Please contact us if you have any need for some NLP in your company. We would be happy to brainstorm with you and figure out the best solution.

Cache is a modern brokerage built for your large stock positions. We are democratizing the financial products used by the ultra-wealthy to manage concentrated stock positions. Do you hold over 10% of your net worth in a single stock? Check out how we can help. -- Cache Securities, LLC is a broker-dealer and Member FINRA/SIPC. Exchange funds are managed by Cache Advisors LLC. Cache Advisors is an investment adviser registered with the Securities and Exchange Commission (“SEC”). Registration does not imply a certain level of skill or training. Cache Advisors and Cache Securities are wholly-owned subsidiaries of Cache Financials Inc. “Cache.” Please review our Terms of Use here: https://usecache.com/legal/terms-of-use

Polymath Robotics makes it radically simple to add autonomous navigation to off-highway vehicles.

Were bringing photonics inside the computer, solving the memory wall and more. To do this, we have to move beyond silicon photonics and rethink what optics looks like. Were backed by Sam Altman, Alex Wang (Scale AI founder), Trevor Blackwell (co-founded YCombinator) and other key AI players.

Open Culture Science builds Habitat™, the personal computer of cell culture, an AI-native hardware platform that automates the growth and analysis of human cell and tissue models. Each desktop-sized system combines microfluidic culture, high-density electrophysiology, and live imaging into a single instrument designed from the ground up to be operated by AI agents rather than pipettes, closing the loop from experimental design to execution to interpretation without a human at every step. Biology has less than 1% of the data needed to model the living cell, and what exists is sparse and under-documented. The bottleneck is no longer reasoning; its the ability to run dense, reproducible experiments on living tissue at scale. Habitat generates that data, and turns it into decisions in real time, on the same sample, across electrical, chemical, and optical axes. The architecture is centralized intelligence with decentralized execution. Every attempt to consolidate the wet lab into one mega-facility has failed because all the specimens, expertise, and instruments cant be co-located. We put a programmable, auditable lab wherever the science is. As the FDA accelerates the shift toward human-relevant, reproducible, traceable data over animal models, Habitat delivers the infrastructure for that era, making biology as shareable, reliable, and collaborative as software.

Extellis is a satellite imaging company dedicated to delivering reliable Earth observations at an industrial scale. Our patented antennas, invented at Duke with DARPA-sponsored research, enable satellites that can take thousands of synthetic aperture radar (SAR) images per day. Blending wide-area scanning with high-volume captures brings advanced spaceborne monitoring capabilities with sensible economics to drive widespread adoption.

At Machine Ventures we invest in startups using computational intelligence as a force-multiplier for humanity.

We combine event-driven distributed architecture with knowledge agents to perform real-time adaptive entity mapping that builds the blueprint for how an organizations knowledge is structured. This blueprint can be accessed by other classes of agents and by humans for entity and relationship resolution across many data and information workflows.

Our Al engine gives your developers the tools to create intelligent agents and workflows that run seamlessly on any hardware- from mobile phones to desktop systems. By enabling local inference for Al Agents, OpenInfer ensures data privacy, significantly reduces costs, and delivers always-available, long-chain reasoning. Unlock the full potential of smart devices everywhere, from robotics to next-generation personal assistants.