Santo Politi

Founder and General Partner at Spark Capital LLC

📍 Boston, Massachusetts, United States🔄 Updated September 2026💼 42 investments📅 29 years investing🗓 Last invested Mar 2025
VC🌍 United States20+ investments
42
Total investments
19
Early stage
8
Mid stage
1
Late stage
29y
Years active

Portfolio

31 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Current Board member
Mar 2025
Bringing the computer to life
Early Investor
Nov 2021
Were on a mission - starting with 100% reusable rockets. At Stoke, we hire the best in the industry, grant them extreme ownership of their work, then celebrate their boundary-pushing speed of innovation. Working as part of a small team means you’ll have greater impact. At Stoke, we move fast, work hard, and have fun building the future of space mobility.
Current Board Member
Oct 2020
Liquidity is the leading AI-driven direct lender globally. Our unique edge is our proprietary technology engine that powers our investment process from origination, underwriting through to exit. With over $2.75 billion in assets under management, Liquidity focuses on providing growth capital to technology companies globally, our process enabling fast and flexible financing that scales with them. Liquidity is backed by leading global financial institutions including Japans largest bank, MUFG, Spark Capital and Apollo Global Management. For more information, visit www.liquidity.com
early stageCapital Markets
Current Board Member
Aug 2019
Droplette is a technology company revolutionizing the skincare industry with its breakthrough device. We are driven by the belief that technology has the power to improve health and wellness, and we are dedicated to creating products and solutions that improve upon the way things have always been done, starting with skincare. Traditional topicals can only do so much. The Droplette device and capsules use our enhanced aerosol technology to deliver active ingredients under the skin - where they can actually work. Droplette was founded in 2017 by two MIT-trained engineers. Over the past 3 years, we have developed the technology and formulations that address consumers’ most common skin concerns. Today, we are a diverse set of domain experts--ranging from engineers and biologists, to dermatologists and skincare industry veterans-- dedicated to helping our customers achieve their skin care goals. #dropletteskin
early stageManufacturing
Current Board Member
Jul 2019
Alpaca is a US-headquartered, self-clearing broker-dealer and a global leader in brokerage infrastructure APIs providing access to stocks, ETFs, options, fixed income, and crypto. Alpaca delivers embeddable finance solutions for tokenization, fully paid securities lending, high-yield cash, 24/5 trading, Shariah-compliant investing, and more. Today, Alpaca powers over 9 million brokerage accounts across hundreds of fintechs and institutions in 40+ countries, with over $320M in funding from top investors including Drive Capital, Portage Ventures, Spark Capital, Tribe Capital, Social Leverage, Derayah Financial, Horizons Ventures, Unbound, SBI Group, Elefund, and Y Combinator.
Current Board Member
Mar 2018
PreVeil makes encryption usable for CMMC & ITAR compliance, business and personal use. PreVeil’s encrypted email works with existing apps like Outlook or Gmail, letting users keep their regular email addresses. PreVeil Drive works like DropBox for file sharing, but with far better security. All messages and documents are encrypted end-to-end, which means that no one other than intended recipients can read or scan them—not even PreVeil. PreVeil is designed for both small teams and large enterprises. Visit www.preveil.com to learn more.
Current Board Member
Dec 2017
We are building the engine that will power discoveries, drive progress, and redefine what computers—and human beings—are capable of.
Current Board Member
Dec 2015
Plaid is a data network that powers the tools millions of people rely on to live a healthier financial life. Plaid works with thousands of companies like Venmo, SoFi, and Betterment, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers more than 12,000 financial institutions across the US, Canada, UK and Europe. Headquartered in San Francisco, the company was founded in 2013 by Zach Perret and William Hockey.
Current Board Member
Jun 2015
Sourcepoint is the practical privacy software company trusted by the worlds most influential brands. Supporting over 30 billion consumer touchpoints per month, Sourcepoint offers enterprise-grade privacy automation for complex, dynamic compliance challenges. We have offices in New York, Berlin, and London.
Current Board Member
Mar 2015
Uncommon pairs experienced recruiters with breakthrough AI technology to find talent quickly, easily, and at very low cost.
early stageHuman Resources
Former Board Member
Mar 2015
Discover and stream the best of movies and TV with a few easy swipes. MightyTV factors in your personal preferences along with the opinions of trusted friends so you spend less time searching, and more time streaming video you’ll love. We employ A.I. to create truly personalized experiences for our users. Choose from a wide variety of streaming services and sort by price. We keep your needs in mind with every swipe. MightyTV launched in April 2016 and is headquartered in New York City.
Current Board Member
Feb 2015
Cybereason is a leading global cybersecurity company. Cybereason provides preparedness and resilience solutions with cutting edge EDR and industry recognized consulting services to support organizations throughout any stage of the incident lifecycle. Cybereason’s award-winning technology and elite experts empower organizations of all sizes to harden, respond and recover from cyber threats in an ever evolving threat landscape. Cybereason is a privately held international company headquartered in California with customers in more than 40 countries.
Current Board Member
Dec 2014
Citizens earn local coins for taking action in their city. Actions as simple as shopping local, recycling, or cycling. Once earned, coins can be redeemed at participating local businesses. Driven by Economic Impact · Powered by Data · Customized by City Colu was founded in 2014 and has raised $35M USD from major VCs. Colu’s app is being used by hundreds of thousands of users and businesses around the world.
Current Board Member
Nov 2013
Orchard is the leading provider of data, technology, and software to the online lending industry. Founded in New York City in 2013, Orchard is building the infrastructure to power the many interactions between originators and institutional investors and help grow online lending into an efficient, transparent, and global financial market.
Former Board Member
May 2013
The Oculus team at Facebook lets people experience anything, anywhere, with anyone through world-class VR hardware and software. With global departments dedicated to VR research, computer vision, haptics, social interaction, and more, Oculus is committed to driving the state of the art forward through relentless innovation. The Oculus suite of hardware currently includes: Rift, our high-end PC VR headset; Touch controllers, to bring your hands into virtual reality; and Gear VR, to bring the magic with you wherever you are—all powered by the Oculus Platform. Since being founded in 2012—and furthered through our acquisition by Facebook in 2014—Oculus has grown from the idea of a single headset to multiple headsets, a powerful platform, and a thriving ecosystem. Our developer community has built nearly a thousand games, apps, and experiences, all available on the Oculus Store. As we continue to grow the possibilities of the technology, we’re partnering with communities and nonprofits from around the world to drive social change and foster a positive impact. VR’s potential to connect the world is immense—and we’re just getting started. For more information, visit: http://oculus.com.
Show all 31 investments ↓
Experience · 45 entries
All (45)
Investments (42)
Founder (1)
Board (41)
2025
Current Board member
Mar 2025
Bringing the computer to life
2021
Early Investor
Nov 2021
Were on a mission - starting with 100% reusable rockets. At Stoke, we hire the best in the industry, grant them extreme ownership of their work, then celebrate their boundary-pushing speed of innovation. Working as part of a small team means you’ll have greater impact. At Stoke, we move fast, work hard, and have fun building the future of space mobility.
2020
Current Board Member
Oct 2020
Liquidity is the leading AI-driven direct lender globally. Our unique edge is our proprietary technology engine that powers our investment process from origination, underwriting through to exit. With over $2.75 billion in assets under management, Liquidity focuses on providing growth capital to technology companies globally, our process enabling fast and flexible financing that scales with them. Liquidity is backed by leading global financial institutions including Japans largest bank, MUFG, Spark Capital and Apollo Global Management. For more information, visit www.liquidity.com
early stageCapital Markets
2019
Current Board Member
Aug 2019
Droplette is a technology company revolutionizing the skincare industry with its breakthrough device. We are driven by the belief that technology has the power to improve health and wellness, and we are dedicated to creating products and solutions that improve upon the way things have always been done, starting with skincare. Traditional topicals can only do so much. The Droplette device and capsules use our enhanced aerosol technology to deliver active ingredients under the skin - where they can actually work. Droplette was founded in 2017 by two MIT-trained engineers. Over the past 3 years, we have developed the technology and formulations that address consumers’ most common skin concerns. Today, we are a diverse set of domain experts--ranging from engineers and biologists, to dermatologists and skincare industry veterans-- dedicated to helping our customers achieve their skin care goals. #dropletteskin
early stageManufacturing
Current Board Member
Jul 2019
Alpaca is a US-headquartered, self-clearing broker-dealer and a global leader in brokerage infrastructure APIs providing access to stocks, ETFs, options, fixed income, and crypto. Alpaca delivers embeddable finance solutions for tokenization, fully paid securities lending, high-yield cash, 24/5 trading, Shariah-compliant investing, and more. Today, Alpaca powers over 9 million brokerage accounts across hundreds of fintechs and institutions in 40+ countries, with over $320M in funding from top investors including Drive Capital, Portage Ventures, Spark Capital, Tribe Capital, Social Leverage, Derayah Financial, Horizons Ventures, Unbound, SBI Group, Elefund, and Y Combinator.
Show all 45 entries ↓
Investment activity
1997–2025 · 42 investments
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