Paul Goldman

Founder & CEO, iTmethods | Govern AI. Own Your Data. Accelerate Everything. The Fortress Family: Forge, Reign & BioCompute.ai | financial, biotech/pharma, defence/space, semiconductor, tech | Advisor & Investor @ intoDNA

πŸ“ United StatesπŸ”„ Updated October 2026πŸ’Ό 1 investmentsπŸ“… 1 years investingπŸ—“ Last invested Sep 2025
Operator-angel🌍 United States
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Strategic Advisor and Investor
Sep 2025
intoDNA is a growing biotech start-up that offers an end-to-end process for DNA break detection with STRIDE, its proprietary technology. It is an innovative technology that outcompetes any other tools in its sensitivity, providing a reliable measure of DNA damage at an individual lesion level.STRIDE has been successfully used by leaders in the biotechnology and pharmaceutical industries and renowned academic groups in DNA damage response, cancer immunotherapy, and nuclear medicine fields.
Experience Β· 3 entries
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Investments (1)
Founder (2)
2025
Founder & CEO
Nov 2025
The Trust Layer for Life Sciences AI AI in pharma isnt waiting for tomorrowβ€”its happening now. But the winners wont be decided by who has the best models. Theyll be decided by who solves for trust, traceability, and audibility. BioCompute is the sovereign AI platform for precision medicineβ€”where every workflow is replayable, every decision is traceable, and every insight is FDA audit-ready. ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ THE BOTTLENECK ISNT AI. ITS TRUST. β†’ Shadow AI proliferating across research teams β†’ Proprietary data training competitors models β†’ Months of compliance prep before every audit β†’ 30-40% patient stratification failures in trials β†’ 4-6 week biomarker validation delays Better models wont solve this. Admissible infrastructure will. ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ WHAT WE BUILT Evidence Engine β€” Immutable audit trails (21 CFR Part 11, IEEE 2791). Every workflow replayable for FDA. Trust isnt a feature; its the architecture. Scientific Workspaces β€” Ephemeral, policy-gated enclaves. Your methods never leave your control. Zero data leakage. Zero shadow AI. Agentic Orchestration β€” Multi-agent workflows for drug discovery and biomarker analysisβ€”with full lineage at every step. NVIDIA Acceleration β€” Inception Member. H100/H200 access. 4-10x speedup without external data exposure. ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ INTODNA STRIDEβ„’ INTEGRATION Native integration with the leading DDR platform for direct, physics-based DNA damage quantification. AstraZeneca-validated. Moving beyond inferred biomarkers to ground-truth functional measurement. ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ DEPLOYMENT Multi-Tenant Β· Dedicated Cloud Β· Air-Gapped ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ 2026 DESIGN PARTNER COHORT β€” Limited spots for pioneers in admissible bio AI. β†’ biocompute.ai Part of The Fortress Family by iTmethods. #PrecisionMedicine #BioAI #SovereignAI #DDR #NVIDIAInception
Strategic Advisor and Investor
Sep 2025
intoDNA is a growing biotech start-up that offers an end-to-end process for DNA break detection with STRIDE, its proprietary technology. It is an innovative technology that outcompetes any other tools in its sensitivity, providing a reliable measure of DNA damage at an individual lesion level.STRIDE has been successfully used by leaders in the biotechnology and pharmaceutical industries and renowned academic groups in DNA damage response, cancer immunotherapy, and nuclear medicine fields.
2005
Founder & CEO
Mar 2005
Bridging the gap between whats possible and whats permissible. iTmethods is the holding company behind the Fortress Family β€” sovereign AI infrastructure for enterprises that cant compromise on security, compliance, or control. For 20 years, weve been the trusted technology backbone for 100+ enterprise customers in financial services, healthcare and Pharma. Today, were helping regulated industries harness AI without sacrificing sovereignty. ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ THE FORTRESS FAMILY 🟠 Forge β€” AI-Native DevOps Platform 55+ DevOps tools, fully managed. Secure AI Gateway, Code Velocity, and enterprise-grade infrastructure. 10-100x developer productivity for teams that cant compromise on security. 🟒 Reign β€” Enterprise AI Governance Control every AI request across your enterprise. 100% visibility, complete compliance. From shadow AI to governed AI in 30 days. MCP-compliant. NIST 800-207 Zero Trust aligned. πŸ”΅ BioCompute β€” Life Sciences AI The Industrial OS for Precision Medicine. From wet-lab chaos to FDA-ready evidence in hours. Native integration with intoDNAs STRIDE platform enables real-time, single-molecule quantitative DNA damage/repair analysis. NVIDIA Inception program member. ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ BY THE NUMBERS - 100+ enterprise customers - 450,000+ users supported - 99.95% platform uptime SLA - 20+ years of enterprise trust - SOC 2 Type II certified ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ INDUSTRIES WE SERVE - Financial Services & Banking - Technology & Semiconductors - Biotech / Pharma / Healthcare - Defense & Spacetech - Energy ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ GLOBAL PRESENCE Hubs in Toronto and Austin, TX, Bangalore, Dublin, and Eastern Europe. Serving enterprise clients across North America and Europe. Were always looking for talented engineers, architects, and specialists passionate about building infrastructure that regulated enterprises can actually trust.