Patrick O'Neill

Medtech Advisor and Investor

📍 Tolland, Connecticut, United States🔄 Updated September 2026💼 8 investments📅 17 years investing🗓 Last invested Jan 2020
VC🌍 United States
8
Total investments
4
Early stage
0
Mid stage
1
Late stage
17y
Years active

Portfolio

5 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Board Member
2020
Lumeda Inc. is a medical technology company advancing photodynamic therapy (PDT) as an adjuvant treatment for patients with non-small cell lung cancer (NSCLC) and other thoracic malignancies. Lumeda’s breakthrough light dosimetry product called DigiLum™ is designed to activate a photosensitizer drug and deliver PDT to reduce the recurrence of cancer and enhance antitumor immunity. DigiLum™ applies advanced photonics and proprietary Artificial Intelligence (AI) software to enable thoracic surgeons to control dosimetry, reduce treatment time and capture data for future treatment planning.
Board Member
2018
CytoVeris is on a mission to enhance the quality intraoperative cancer detection through AI-powered imaging solutions, improving outcomes and accessibility to surgeons and patients alike. Learn more about our Smart Cancer Imaging Platform at www.cytoveris.com.
Board Observer
2017
Who We Are: LindaCare, a digital health company specialized in the development of integrated remote-monitoring software solutions for cardiovascular and chronic disease management What We Do: We provide healthcare professionals and hospitals with a single integrated and unified vendor independent software platform, making patient remote-monitoring significantly more efficient and enhancing the quality of patient care Our Vision: One day, every patient with a chronic disease will have peace of mind and better quality of life, knowing his health condition is being monitored, anywhere, anytime, all the time Our Focus: Patients with Chronic Heart Failure and Cardiac Arrhythmia who have Cardiac Implanted Electronic Devices for Cardiac Rhythm Management Our Story: LindaCare is the result of a Hack-a-thon, organized by Microsoft Innovation Center, attended by our owner and founder Shahram Sharif. His group listened to the intense frustrations of a nurse named Linda. At the time, she was finding it difficult to monitor her patients remotely because the systems used by nurses and doctors across all hospitals and clinics, weren't the same. We made it easy for people like Linda to observe her patients with our single, unified software platform. On one dashboard, Linda could view those who had remote monitoring data from different cardiac device vendors. Her workflow became more efficient due to built-in automation which assimilates into electronic health records. She could also see which patients needed the most attention and how quickly as well as their health history. The results were faster action, quicker reporting and lower re-admission rates for her patients Our Culture: The ART oF Joy * Ambition * Recognition * Trust * Freedom * Joy Because at LindaCare, we want everyone to Enjoy Life More!
Board Observer
2016
r4 is the pioneer of cross-enterprise AI. Organizations across multiple industries use r4’s platform to unlock growth opportunities trapped in and between enterprise silos, systems, and processes. Cross-enterprise AI does that by bringing together data from across the enterprise, regardless of location or format, in a secure private cloud. Then it adds external data – on customer segments, locations, distribution models, and many other variables—to create a completely new and unified model of a business and its markets. Cross-enterprise AI deeply analyzes this information, uncovers new revenue opportunities that could never be seen before, and delivers a set of predictions and targeted recommendations that can be automatically fed back into enterprise systems as instructions. r4 was created by the founders of priceline.com and key Priceline executives to leverage Priceline’s breakthroughs in applying predictive algorithms on a mass scale to extract profit from data. Their vision and innovations pioneered e-commerce as a business model and revolutionized the travel industry. The r4 team is now applying this same DNA to help large companies apply cross-enterprise AI to drive growth and create competitive advantages. r4's operations are headquartered in Connecticut, with presence in Metropolitan New York, San Francisco, Austin and Washington, DC. European operations are headquartered in Dublin, with presence in Munich and London.
Board Observer
2009
SmartEquip is the leading technology standard for equipment lifecycle management, service and procurement support for the construction industry. The platform provides a multi-brand common connection and user experience for fleet owners and distributors of complex equipment. SmartEquip enhances ROI for all Network participants by increasing equipment uptime, improving both technician wrench time and transaction accuracy, while reducing the total cost of equipment ownership. The SmartEquip Network currently supports more than 500 OEM brands, with over 50,000 users across more than 4,000 equipment locations globally. The Network supports over $1 billion in parts transactions annually and the company is led by veterans of construction, technology and data sciences. Founded in 2000, SmartEquip is positioned to define tomorrows dynamic and evolving equipment industry.
Experience · 10 entries
All (10)
Investments (8)
Board (8)
2025
Imaginostics
Vice President, Strategic Partnerships
2025
2020
Board Member
2020
Lumeda Inc. is a medical technology company advancing photodynamic therapy (PDT) as an adjuvant treatment for patients with non-small cell lung cancer (NSCLC) and other thoracic malignancies. Lumeda’s breakthrough light dosimetry product called DigiLum™ is designed to activate a photosensitizer drug and deliver PDT to reduce the recurrence of cancer and enhance antitumor immunity. DigiLum™ applies advanced photonics and proprietary Artificial Intelligence (AI) software to enable thoracic surgeons to control dosimetry, reduce treatment time and capture data for future treatment planning.
2019
Board Observer
2019
Budderfly, the fastest-growing Energy Efficiency as a Service (EEaaS) company in the United States, is the premier sustainability partner for businesses with repeatable footprints, such as restaurant chains, assisted living facilities, retail franchises, and more. Budderfly installs, monitors, and manages a combination of patented technologies, equipment upgrades, and proprietary energy software for its customers at no out-of-pocket cost. Businesses benefit with lower energy bills, a reduced carbon footprint, more reliable operations, and an improved customer and employee experience. Budderfly ranked #2 in energy companies and #10 overall on the 2021 Inc. 5000 America’s Fastest-Growing Private Companies list.
EnviroPower
Board Member
2019
2018
Board Member
2018
CytoVeris is on a mission to enhance the quality intraoperative cancer detection through AI-powered imaging solutions, improving outcomes and accessibility to surgeons and patients alike. Learn more about our Smart Cancer Imaging Platform at www.cytoveris.com.
Show all 10 entries ↓
Investment activity
2009–2020 · 8 investments
200912016220171201812019220201
Recent (last 2 years)Earlier