Mario Scuderi

Angiodroid SpA is an Italian innovative Company that projects and trades solutions for the medical market. Angiodroid® The CO2 Injector is our main product. It is a Carbon Dioxide (CO2) Injector for Interventional Radiology procedures and represents the perfect solution for the treatment of patients with: • Contrast Induced Nephropathy (CIN) risk • Diabetic Disease • Renal Failure • Intolerance to Iodinated contrast media The use of CO2 in Peripheral Angiography has been common practice for many decades. To date, however, it has not the proper success due to the lack of advanced technology which could support operators during the procedures. Until now, the market solution was the use of manual injection kits (that means no procedural repeatability, no control of injection pressure and air contamination risk). Angiodroid® The CO2 Injector, whose main fields of application are Interventional Radiology & Vascular Surgery, is the perfect solution to all these problems and is the only injector: • 100 % automatic • 100 % safe • 100 % digital • 100 % user friendly More info at www.angiodroid.com

BeDimensionals mission is to become the world leader in the production of two-dimensional (2D) materials such as graphene. We exploit a unique patented production process able to manufacture on a large scale pristine materials having atomic thickness and displaying exceptional electrical thermal and mechanical properties. 2D materials represent a novel class of super additivies that will revolutionize the global manufacturing industry in applications such as batteries, lubricants, coatings.

WSENSE is a spin-off of Sapienza University of Rome, with a strong and experienced R&D team specialized in monitoring and communication systems with pioneering patented solutions in the Internet of Underwater Things (IoUT). WSENSE has been founded in 2012 by Prof. Chiara Petrioli, leading Sapienza PhD Program in Computer Science, Sapienza SENSES Lab and Sapienza Cyber Physical System Lab. WSENSE offers complete solutions, building on the customer’s needs and WSENSE innovative monitoring and communication technologies to provide affordable value to assets our customers have already invested in, adding functionality to current systems, increasing profitability and competitiveness. WSENSE breakthrough Internet of Underwater Things solutions guarantee a complete cableless networking interoperability among various vendors of underwater sensors and autonomous vehicles (UAV, ASV, AUV), ensuring real-time monitoring and an extensive surveillance of underwater environments, waterways and marine seabeds. WSENSE solutions support Blue Growth’s long term strategy in the marine and maritime sectors as a whole and sustain companies to be more “eco-innovative” with a marked reduction in cost and a significant increase in value, in terms of market share and brand reputation.

Here at Eggtronic, we design power electronics that are redefining the future of wired and wireless power conversion. Because of the versatility and excellent performance of EPIC, our proprietary family of mixed-signal, low-power, cost-optimized power conversion controllers, our custom-designed ASICs deliver power conversion and wireless power transfer applications in a quick, energy-efficient and cost-effective manner. We also provide manufacturing support for accelerated mass production of custom products, as well as off-the-shelf solutions, based on Eggtronic ICs. Whether through B2B partnerships in the consumer, automotive or industrial markets, or for everyday consumers, Eggtronic technologies help make modern life easier, more efficient and more connected.

Sibylla is an innovative start-up founded in 2017 as a spin-OFF of the INFN (National Institute of Nuclear Physics) and the Trento and Perugia Universities. Its multidisciplinary team of co-founders has developed a pioneering Early Drug Discovery method that applies to the research and design of new drugs, effective against diseases so far incurable. Drug discovery is an extremely complex problem, therefore requiring innovation. Sibylla is a beautiful example of how innovation can be pushed forward by a multidisciplinary and agile team. Sibylla's approach is based on the possibility of simulating the folding pathway from the amino acid sequence as produced by the cells' ribosomes to the native state. Traditional pharmacological methods investigate the target proteins' interaction sites in their native, biologically active state. Novel methods act at the DNA level. Sibylla follows an alternative approach. We identify small molecules that bind to pockets found in the intermediate folding state. These pockets disappear in the native state, and that is why we may try to drug proteins which have been so far considered undruggable. Sibylla technology is called PPI-FIT (Pharmacological Protein Inactivation by Folding Intermediate Targeting). A molecule found through PPI-FIT would impair the folding of the protein, leading it to degradation. The overall effect is a selective reduction of the expression level of the target protein. The medical areas focused on by Sibylla's research include oncology and antibiotic resistance, although the technology can be applied to any therapeutic area. The company is developing a proprietary pipeline of potential drugs. We can also provide co-development or identifying potential drugs for pharmaceutical companies' specific targets. We recently signed a collaboration agreement with an important Pharma company. Besides the promising results already achieved, Sibylla keeps being engaged in developing proprietary computing technology.

Thanks to a deep and many years of experience in the field of Defense, we have created an extremely innovative solutions to protect the strategic IT/OT resources of public and private companies. The goal achieved was to introduce a different level of Cyber ​​Security through an "all-in-one" system, for any type of device and operating system, enhanced by a sophisticated AI supervision and automatic reaction system, capable of ensuring the stability and resilience of IT/OT environments. We are an Italian Company, a security vendor that develops highly scalable, modular and customizable Cyber Security solutions. We are a Technology Partner for System Integrators, Advisory Companies and Solution Providers.

Energy Dome is a company with revolutionary technology for large scale and long duration energy storage. Our proprietary technology is based on a thermodynamic process that uses CO2 to store electricity cost-effectively with unprecedented round-trip efficiencies. The simplicity of the process as well as the use of readily available off-the-shelf equipment opens the way for Energy Dome to quickly become an important player in the energy storage market. With our technology it is possible to store large quantities of energy for long periods of time anywhere without any site dependency and deliver all the typical services of utility-scale storage systems, including grid regulation services, maximizing investment returns for our customers.

Rubber Conversion s.r.l. is a recognized Italian technology company bringing a cutting edge devulcanization process to service the needs for high quality sustainable compounds of European tire and technical rubber goods manufacturers. Rubber Conversion produces high quality sustainable rubber compounds from production off-cuts and end of life rubber products. Rubber conversion uses an innovative, patented technology for devulcanizing rubber compounds. The technology is based on a ambient-temperature, ambient-pressure mechanical shear process, activated by a green, powdered devulcanizing agent, that selectively breaks sulphur crosslinks leaving the mechanical properties of the compound intact. The process has a low carbon footprint and it is environmentally friendly Rubber Conversion’s commitment to material recycling and upcycling is helping mindful companies improve their product sustainability and profitability. Rubber Conversion is a subsidiary company of Innovando, a leading Italian company providing global service solutions for industrial waste management and extended producers responsibility compliance services to SMEs and large corporations.

Diadem’s goal is to be the first truly blood-based Prognostic (Px) test for early detection of dementia in Neurodegenerative disease with a particular focus to Alzheimer’s Disease. Diadem has developed a unique/novel solution to one of the biggest problems in Neurodegenerative disease and in particular in early, accurate, predictive, fast, non-invasive and cost effective diagnosis in Alzheimer’s disease, which should enable improve treatment and the overall improvement in patient treatment/outcomes. Diadem was founded in 2012 as a spin-off of University of Brescia (Italy) and preparing for rapid commercialisation of its product via a global launch with strategic partners in 2021, additionally the Company is planning to carrying out further retrospective and prospective clinical trials to further validate its clinical claims.

IAMA Therapeutics is a preclinical-stage pharmaceutical company focused on discovering, developing, and commercializing novel medicines to make a difference in the lives of children and adults suffering from neurodevelopmental and cognitive disorders. IAMA Therapeutics couples emerging advances in drug discovery and neurobiology to build a leading, next-generation neuroscience pipeline to selectively inhibit the sodium-potassium chloride cotransporter and other therapeutic targets relevant to brain disorders characterized by neuronal imbalance. The company's preclinical pipeline consists of the lead candidate IAMA-6 for the treatment of idiopathic autism, IAMA-097 for the treatment of secondary autism, and other compounds for the treatment of refractory epilepsy and other brain disorders. IAMA-6 is a preclinical stage, a first-in-class selective-NKCC1 inhibitor that modulates the intracellular chloride, reducing the depolarizing strength of GABAA receptors to the levels required to restore the inhibitory transmission. This pathway is reported in Down syndrome, autism spectrum disorder, epilepsy, and other brain disorders characterized by increased intracellular chloride and depolarizing GABAergic transmission.

Cubbit empowers any organisation to create its own S3 cloud storage in minutes from a single intuitive interface: geo-distributed resilience, sovereign control, and up to 80% savings vs. hyperscalers. Data is encrypted, fragmented, and replicated across locations of your choice: never exposed in full, always accessible. Run it on your own infra or rented resources (e.g., bare-metal), or adopt fully-managed S3 cloud storage hosted and operated in Europe by our certified partners. 100% European technology: free from extraterritorial laws, data localisation down to your own perimeter, and designed for hybrid and multi-cloud diversification. Backup, AI storage, edge cases… 400+ enterprises and service providers have taken back control over their data, IT stack, and costs.

Talent Garden is Europes leading digital skills academy and founding partner of a global EdTech group, that provides individuals and organisations with the knowledge, spaces and resources needed to transform and thrive within the innovation ecosystem. They offer diverse learning experiences with online, offline and hybrid courses, corporate programs and events and a network of coworking campuses that hosts a vibrant community of digital and tech professionals. Founded in Italy in 2011, Talent Garden’s mission is to empower people and organisations to drive digital transformation through life-changing learning and networking experiences. With an unparalleled vision to combine work life and learning. Talent Garden has already significantly impacted and uplifted professionals and corporations by closing the digital skills gap, training over 25,000 professionals in digital design, marketing, data and hard skills, human resources, business innovation, product management, and cyber security. As one of the fastest-growing companies in Europe, Talent Garden also develops tailored corporate education programs leveraging their expertise in digital transformation and a network of partners such as Google, Procter & Gamble, Cisco, Unilever, leading European banks, institutions and other companies in the Fortune 500 ranking. These transformative experiences go beyond the classroom, with the company enabling powerful connections within the digital and tech ecosystem. Thanks to a network of coworking campuses in 13 countries (Austria, Brazil, Denmark, France, Ireland, Italy, Lithuania, North USA, Singapore, Spain, Sweden, Switzerland and the UK) that hosts not only students but over 45,000 innovators from startups, agencies, corporate labs, freelancers, and SMEs, who are all united by a like-minded vision for digital innovation. Open 24 hours a day, these campuses are designed to encourage collaborations and provide professionals with a physical base to succeed and scale.

Talent Garden is Europe's leading digital skills academy that has combined work life and learning to empower people and organisations through transformative experiences. We provide diverse learning experiences with online, offline and hybrid digital skills courses and have a growing community of over 25,000 alumni. We have supported over 180 organisations with corporate training programs and host Europe's largest digital and tech community with over 4,500 professionals within a network of workspaces in campuses across seven countries. Unlock your highest potential today and join our community of continuous learners.

WeSchool is the leading Italian EdTech startup. We are on a mission to ensure learning never stops by empowering educators and students to innovate learning by making it more inclusive, collaborative and engaging way of learning. WeSchool partners with the most important Italian and global companies in the banking, ICTs, energy and publishing industries to close the gap between education and the future of work. We transfer organizations' know how to students in schools to increase their engagement, motivation and commitment in building the world of tomorrow. We provide a collaborative learning platform that, during the outbreak of the COVID19 pandemic, has enabled 1.7M (20% of) Italian students not to miss school - the only Italian platform among the three recommended by the Italian Ministry of Education, the other 2 platforms being Google and Microsoft - and to amplify their learning experience by leveraging digital tools. Founded in 2016, WeSchool has recently closed a Series A funding round (P101, Azimut, CDP Venture Capital, TIM Ventures).

Empatica is an affective computing company, focused on human data analytics. We develop groundbreaking wearable devices with medical quality sensing. Our technology comprises a set of wristband, software running on smartphone and desktop computing, plus real time syncing with a cloud computing service.

Angiodroid SpA is an Italian innovative Company that projects and trades solutions for the medical market. Angiodroid® The CO2 Injector is our main product. It is a Carbon Dioxide (CO2) Injector for Interventional Radiology procedures and represents the perfect solution for the treatment of patients with: • Contrast Induced Nephropathy (CIN) risk • Diabetic Disease • Renal Failure • Intolerance to Iodinated contrast media The use of CO2 in Peripheral Angiography has been common practice for many decades. To date, however, it has not the proper success due to the lack of advanced technology which could support operators during the procedures. Until now, the market solution was the use of manual injection kits (that means no procedural repeatability, no control of injection pressure and air contamination risk). Angiodroid® The CO2 Injector, whose main fields of application are Interventional Radiology & Vascular Surgery, is the perfect solution to all these problems and is the only injector: • 100 % automatic • 100 % safe • 100 % digital • 100 % user friendly More info at www.angiodroid.com

BeDimensionals mission is to become the world leader in the production of two-dimensional (2D) materials such as graphene. We exploit a unique patented production process able to manufacture on a large scale pristine materials having atomic thickness and displaying exceptional electrical thermal and mechanical properties. 2D materials represent a novel class of super additivies that will revolutionize the global manufacturing industry in applications such as batteries, lubricants, coatings.

WSENSE is a spin-off of Sapienza University of Rome, with a strong and experienced R&D team specialized in monitoring and communication systems with pioneering patented solutions in the Internet of Underwater Things (IoUT). WSENSE has been founded in 2012 by Prof. Chiara Petrioli, leading Sapienza PhD Program in Computer Science, Sapienza SENSES Lab and Sapienza Cyber Physical System Lab. WSENSE offers complete solutions, building on the customer’s needs and WSENSE innovative monitoring and communication technologies to provide affordable value to assets our customers have already invested in, adding functionality to current systems, increasing profitability and competitiveness. WSENSE breakthrough Internet of Underwater Things solutions guarantee a complete cableless networking interoperability among various vendors of underwater sensors and autonomous vehicles (UAV, ASV, AUV), ensuring real-time monitoring and an extensive surveillance of underwater environments, waterways and marine seabeds. WSENSE solutions support Blue Growth’s long term strategy in the marine and maritime sectors as a whole and sustain companies to be more “eco-innovative” with a marked reduction in cost and a significant increase in value, in terms of market share and brand reputation.

Here at Eggtronic, we design power electronics that are redefining the future of wired and wireless power conversion. Because of the versatility and excellent performance of EPIC, our proprietary family of mixed-signal, low-power, cost-optimized power conversion controllers, our custom-designed ASICs deliver power conversion and wireless power transfer applications in a quick, energy-efficient and cost-effective manner. We also provide manufacturing support for accelerated mass production of custom products, as well as off-the-shelf solutions, based on Eggtronic ICs. Whether through B2B partnerships in the consumer, automotive or industrial markets, or for everyday consumers, Eggtronic technologies help make modern life easier, more efficient and more connected.

Sibylla is an innovative start-up founded in 2017 as a spin-OFF of the INFN (National Institute of Nuclear Physics) and the Trento and Perugia Universities. Its multidisciplinary team of co-founders has developed a pioneering Early Drug Discovery method that applies to the research and design of new drugs, effective against diseases so far incurable. Drug discovery is an extremely complex problem, therefore requiring innovation. Sibylla is a beautiful example of how innovation can be pushed forward by a multidisciplinary and agile team. Sibylla's approach is based on the possibility of simulating the folding pathway from the amino acid sequence as produced by the cells' ribosomes to the native state. Traditional pharmacological methods investigate the target proteins' interaction sites in their native, biologically active state. Novel methods act at the DNA level. Sibylla follows an alternative approach. We identify small molecules that bind to pockets found in the intermediate folding state. These pockets disappear in the native state, and that is why we may try to drug proteins which have been so far considered undruggable. Sibylla technology is called PPI-FIT (Pharmacological Protein Inactivation by Folding Intermediate Targeting). A molecule found through PPI-FIT would impair the folding of the protein, leading it to degradation. The overall effect is a selective reduction of the expression level of the target protein. The medical areas focused on by Sibylla's research include oncology and antibiotic resistance, although the technology can be applied to any therapeutic area. The company is developing a proprietary pipeline of potential drugs. We can also provide co-development or identifying potential drugs for pharmaceutical companies' specific targets. We recently signed a collaboration agreement with an important Pharma company. Besides the promising results already achieved, Sibylla keeps being engaged in developing proprietary computing technology.