Jesse Cole

Synthesis Ventures

📍 New York, New York, United States🔄 Updated September 2026💼 8 investments📅 8 years investing🗓 Last invested Apr 2026
VC🌍 United StatesInvested this year
8
Total investments
3
Early stage
1
Mid stage
0
Late stage
8y
Years active

Portfolio

7 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Investor
Apr 2026
Scout AI is a frontier AI lab for U.S. defense. It was founded in 2024 by Colby Adcock and Collin Otis with a mission to deploy mission-ready AI agents across unmanned systems for the Department of War and its allies. Its Fury foundation model transforms uncrewed ground, air, sea, and space platforms and payloads into intelligent, collaborative teammates that multiply warfighter effectiveness. Scout AI is based in Sunnyvale, CA and is backed by leading institutional investors including Booz Allen Ventures, Align Ventures, Draper Associates, and Perot Jain.
Investor
Feb 2026
Wip™ is building a new standard in energy – creating breakthrough products that deliver performance, portability, and purpose for people on the move. Our energy pouches are crafted with natural caffeine, vitamins, and minerals in a format that meets real-life needs. We’re a category-defining, culture-shaping company with world-class product development, scaled manufacturing, and best-in-class commercialization. Our ambition is big: to redefine what energy means and how it’s delivered.
Investor
Dec 2025
Reflection is a research lab making intelligence open and accessible for everyone to use, customize, and build on. Our team previously built frontier LLMs at labs like DeepMind, OpenAI, and Anthropic. We believe AI should be built in the open, with transparent research and collaborative development. That means giving enterprises, governments, and sovereign entities true ownership and control of AI that performs at the highest level. Our mission: make intelligence open and accessible to all.
Executive Advisor and Investor
May 2024
Making extinction a thing of the past. Colossal is a breakthrough bioscience and genetic engineering company that builds radical new technologies to advance the field of genomics. Colossal creates disruptive technologies for extinct species restoration, critically endangered species protection and the repopulation of critical ecosystems that support the continuation of life on Earth. The company is the first to apply CRISPR technology for the purposes of species de-extinction. Colossal is accepting humanity’s duty to restore Earth to a healthier state, while also solving for the future economies and biological necessities of the human condition through cutting-edge science and technologies.
Investor
Jan 2022
Transforming the in-home coffee experience, starting with a new coffee machine. Conscious, clean, and carefully crafted.
mid stageManufacturing
Board Member
Nov 2018
VERITUS GROUP - Consulting and advising consumer companies / platforms in the development of their growth strategy (e.g. corporate infrastructure, merchandising, supply chain, distribution (wholesale / retail / DTC), as well as setting a clear pathway and successfully executing a monetization event for existing shareholders. VERITUS CAPITAL - Deploying growth capital and debt financing to emerging consumer companies / platforms.
Board Member
Oct 2018
We received our first funding! Watch for updates shortly. Lots of changes are coming soon!
Experience · 13 entries
All (13)
Investments (8)
Founder (2)
Board (2)
2026
Investor
Apr 2026
Scout AI is a frontier AI lab for U.S. defense. It was founded in 2024 by Colby Adcock and Collin Otis with a mission to deploy mission-ready AI agents across unmanned systems for the Department of War and its allies. Its Fury foundation model transforms uncrewed ground, air, sea, and space platforms and payloads into intelligent, collaborative teammates that multiply warfighter effectiveness. Scout AI is based in Sunnyvale, CA and is backed by leading institutional investors including Booz Allen Ventures, Align Ventures, Draper Associates, and Perot Jain.
Investor
Feb 2026
Wip™ is building a new standard in energy – creating breakthrough products that deliver performance, portability, and purpose for people on the move. Our energy pouches are crafted with natural caffeine, vitamins, and minerals in a format that meets real-life needs. We’re a category-defining, culture-shaping company with world-class product development, scaled manufacturing, and best-in-class commercialization. Our ambition is big: to redefine what energy means and how it’s delivered.
2025
Investor
Dec 2025
Reflection is a research lab making intelligence open and accessible for everyone to use, customize, and build on. Our team previously built frontier LLMs at labs like DeepMind, OpenAI, and Anthropic. We believe AI should be built in the open, with transparent research and collaborative development. That means giving enterprises, governments, and sovereign entities true ownership and control of AI that performs at the highest level. Our mission: make intelligence open and accessible to all.
Executive Advisor and Investor
May 2025
They say that by 2050, there will be more plastic in the ocean than fish by weight. We say that by 2050, there will be more fish in the ocean than plastic by weight. PATH is on a mission to redefine sustainability by putting a refillable bottle in the hands of every individual and encouraging humanity to break free from single-use plastic. Our REvolution grows daily, propelled by the global consumer demand for sustainable and reusable alternatives in bottled water packaging. Our commitment to sustainability extends to teaming up with other brands to curb their plastic waste. Through our Co-Brand Program, we collaborate with corporations giving them a tangible initiative and a sleek cobranded bottle to increase reuse. Our partners proudly display their commitment to change, signaling to the world that their brand is part of the solution to #refillit. We’re thrilled about our Partnerships to Save the Planet with a growing brand roster that includes 1Hotel, 4 Seasons, State Farm, Intuit, Facebook, Rivian, Enphase, Lockheed Martin, 7-Eleven, Dropbox, 10 Tree, Kayak, Hasbro, Nickelodeon, MLB Post Season, Adidas, California Science Center, San Francisco State University, Wisconsin Union, Yellowstone National Park, Orangetheory Fitness, and Barrys. Join the REvolution to #refillit!
2024
Co-Founder
Sep 2024
Synthesis prioritizes investments that harmonize societal good and financial gains to make the world a better place: healthier, happier, longer-living consumers and more productive, more efficient, more equitable businesses. We focus on seed-stage investments in software companies but will selectively invest in consumer and hardware ventures. We lead, co-lead, and follow with checks ranging from $500,000 to $2 million.
Show all 13 entries ↓
Investment activity
2018–2026 · 8 investments
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