Jonathan Hirsch

CSO and founding team at Paradigm

📍 San Francisco Bay Area, United States🔄 Updated September 2026💼 13 investments📅 6 years investing🗓 Last invested Sep 2024𝕏 @upgrade_to_unlock
VC🌍 United States
13
Total investments
7
Early stage
1
Mid stage
0
Late stage
6y
Years active

Portfolio

12 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Seed Investor
Sep 2024
The biggest unmet need in AI today is getting access to the right training data. Data holders often don’t know where to start and are rightly concerned about governance, intellectual property, and security implications. AI companies can spend years finding and negotiating access to the data they need. Protege is solving these problems by providing an easy-to-use platform to connect data holders with vetted data users.
Investor
Jan 2024
At Arbital Health, we’re transforming value-based care, one contract at a time. Our actuarial science-powered platform centralizes, measures, and adjudicates contracts at scale, providing the transparency and precision needed for success. With data-driven tools and actuarial advisory services, we help our partners achieve financial stability while delivering high-quality care. We believe incentive alignment is one of the most important challenges in the US healthcare system. By building the neutral, third-party adjudication utility to help bolster outcomes-based healthcare contracts, we believe that Arbital will accelerate the $1 trillion dollar shift to value-based care in the US. Arbital Health is a new, well-funded healthcare technology startup founded by an experienced team with multiple successful exits in the healthcare industry over the past fifteen years.
Seed Investor
Nov 2023
Were building the future of surgical care—one that’s surgeon-led, tech-powered, and value-based by design. In creating and deploying the first vertically integrated surgical care system - combining AI and technology with operationally excellent surgical centers - Oath Surgical delivers high quality care that’s better, faster, and more affordable for patients, providers, and payors. Oath Surgical offers a rare proof point for how value-based care can work and scale in the real world.
Seed Investor
Oct 2023
Solstice is an AI engine for life sciences marketing teams that accelerates the creation, evaluation, and distribution of personalized content. We allow pharmaceutical brand teams to rapidly deploy compliant content at-scale.
Seed Investor
Sep 2023
Proactive primary care that scales with AI. YC S23.
Seed Investor
Mar 2023
Were building towards a world where hospital operations are safe, autonomous, fair, and cost-effective. Hospitals still run their most important operations—staffing, labor planning, and capacity—on paper, spreadsheets, and guesswork. The result: thousands of wasted hours, millions in unnecessary labor spend, and frontline teams stretched thin. Vitalize replaces this with intelligent, automated staffing operations to align labor supply with patient demand. Our platform gives clinical leaders real-time decision support to reduce manual work, lower labor costs, and unlock patient capacity across the enterprise. We are trusted by top health systems across the country, and have raised from top healthcare and technology investors.
Co-Founder, Investor, and Chair of the Advisory Board
Feb 2022
Synapticure brings expert virtual care to individuals and caregivers living with neurodegenerative diseases, including Parkinsons, Alzheimers and related dementia, ALS, and more conditions. Our mission is to democratize access to cutting-edge and personalized care provided by neurologists, mental health providers, and care navigators here for you 24/7.
Investor
Feb 2022
Forta is clearing the path to quality healthcare. We continuously improve the patient journey and deliver personalized care by applying AI and machine learning. The first care vertical Forta is improving is autism ABA therapy. Care is difficult to access and the delivery model must be reinvented to provide early access to families. 1 in 44 children [CDC, 2021] is diagnosed to be on the autism spectrum. We are looking for driven, innovative, patient-focused individuals to join our team as we reinvent the care and tools available to neurodiverse families.
Investor
Oct 2021
Frame is the first collaborative care platform for fertility and family building. Frame partners with healthcare providers, employers and payers to provide members with holistic care, coaching and 1:1 support, improving outcomes and lowering costs for everyone involved. Founded by a wife and husband team that went through their own challenging fertility journey, Frame seeks to displace reactive, one-size-fits-all family building models, offering a new way forward guided by fertility experts who get where youre coming from and lead you where you want to go. Frame supports people of all races, ethnicities, gender identities and sexual orientations, both single and partnered.
Investor and Advisory Board
Jun 2021
Thyme Care is a value-based oncology management platform whose mission is to improve the quality of life for people diagnosed with cancer by providing personalized, clinically coordinated care. Thyme Care pairs human guidance with software and analytics to quickly connect members to the right care and provide ongoing support through targeted, evidence-based interventions. Founded by oncology industry veterans and clinicians, the companys approach prioritizes deep provider relationships and integrates with a health plan’s existing infrastructure, coordinating value-driven care that leads to better outcomes, lower costs, and an improved member experience. Backed with venture funding from Andreessen Horowitz (a16z), AlleyCorp, Frist Cressey Ventures, Casdin Capital, and Bessemer, Thyme Care partners with health insurance plans and providers to extend the reach of high-quality cancer care through flexible value-based payment arrangements, including risk-based programs. To learn more about how Thyme Care is unlocking high-value care in oncology, visit www.thymecare.com.
Strategic Advisor and Investor
Oct 2020
Osmind is a San Francisco–based public benefit corporation led by scientists, technologists, and psychiatrists to advance new evidence-generating medicine that helps people living with moderate to severe mental health conditions. For more information, please visit osmind.org. Were hiring! Learn more at osmind.org/careers
Investor
Aug 2020
Verifiable is an API-first, provider network management platform built to help healthcare provider and payer organizations speed up network operations, save costs and streamline the provider experience. Verifiable industry-leading provider data infrastructure connects to thousands of primary sources to deliver real-time provider verification & monitoring to automate the credentialing process - resulting 78% faster turnaround times and millions in added revenue capture. Verifiable works with innovative healthcare provider and payer organizations like Humana, Lyra Health, Talkspace, Modern Health, Wheel, Grow Therapy, and many others. Verifiable is a proud Y-Combinator company whose investors include Craft Ventures, Highland Capital Partners, Tiger Global, The Altman Fund, Struck Capital, Liquid2 Ventures, 137 Ventures, Cooley and Soma Capital.
Experience · 19 entries
All (19)
Investments (12)
Founder (2)
2024
Seed Investor
Sep 2024
The biggest unmet need in AI today is getting access to the right training data. Data holders often don’t know where to start and are rightly concerned about governance, intellectual property, and security implications. AI companies can spend years finding and negotiating access to the data they need. Protege is solving these problems by providing an easy-to-use platform to connect data holders with vetted data users.
Investor
Jan 2024
At Arbital Health, we’re transforming value-based care, one contract at a time. Our actuarial science-powered platform centralizes, measures, and adjudicates contracts at scale, providing the transparency and precision needed for success. With data-driven tools and actuarial advisory services, we help our partners achieve financial stability while delivering high-quality care. We believe incentive alignment is one of the most important challenges in the US healthcare system. By building the neutral, third-party adjudication utility to help bolster outcomes-based healthcare contracts, we believe that Arbital will accelerate the $1 trillion dollar shift to value-based care in the US. Arbital Health is a new, well-funded healthcare technology startup founded by an experienced team with multiple successful exits in the healthcare industry over the past fifteen years.
2023
Seed Investor
Nov 2023
Were building the future of surgical care—one that’s surgeon-led, tech-powered, and value-based by design. In creating and deploying the first vertically integrated surgical care system - combining AI and technology with operationally excellent surgical centers - Oath Surgical delivers high quality care that’s better, faster, and more affordable for patients, providers, and payors. Oath Surgical offers a rare proof point for how value-based care can work and scale in the real world.
Seed Investor
Oct 2023
Solstice is an AI engine for life sciences marketing teams that accelerates the creation, evaluation, and distribution of personalized content. We allow pharmaceutical brand teams to rapidly deploy compliant content at-scale.
Seed Investor
Sep 2023
Proactive primary care that scales with AI. YC S23.
Show all 19 entries ↓
Investment activity
2020–2024 · 13 investments
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