JC

Jason Coloma

Maze Therapeutics

📍 San Francisco Bay Area, United States🔄 Updated September 2026💼 5 investments📅 8 years investing🗓 Last invested Aug 2021
VC🌍 United States
5
Total investments
2
Early stage
0
Mid stage
1
Late stage
8y
Years active

Portfolio

3 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Board Member
Aug 2021
BioAge is a clinical-stage biopharmaceutical company developing therapeutic product candidates for metabolic diseases by targeting the biology of human aging. The Companys lead product candidate, BGE-102, is a potent, orally available, brain-penetrant small-molecule NLRP3 inhibitor being developed for cardiovascular risk and retinal diseases. A Phase 1 SAD/MAD trial of BGE-102 is underway, with topline data including additional MAD cohorts anticipated in 1H26. The Company is also developing long-acting injectable and oral small molecule APJ agonists for obesity. BioAge’s additional preclinical programs, which leverage insights from the Company’s proprietary discovery platform built on human longevity data, address key pathways involved in metabolic aging. BioAge offers a comprehensive compensation package, comprehensive health and wellness benefits (medical, dental, and vision insurance), childcare and fertility benefits, and a 401(k) retirement savings plan with matched employer contributions. We pride ourselves on giving employees many opportunities for career development, including a generous annual budget for continued learning and dedication to training and skill development. At BioAge, everyone matters, and we embrace diversity and differences while we learn from each other. We are an equal opportunity employer. BioAge prohibits discrimination and harassment of any type and affords equal employment opportunities to employees and applicants without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. BioAge conforms to the spirit as well as the letter of all applicable laws and regulations.
Board Member
May 2019
Developing next generation mRNA immunotherapies
Board Member
Nov 2018
Alloy Therapeutics is a biotechnology ecosystem company empowering the global scientific community to make better medicines together. From licensing our platforms, to working with us as a trusted discovery service partner, we have collaborated with over 170+ partners and counting including 18 of Fortune 50 Biopharmaceutical companies to enable the discovery of their next breakthrough biologic medicines. With Alloy, you can: • Access our ever-growing stable of antibody and bispecific discovery platforms that blend in vivo and in vitro wet-lab capabilities with AI/ML. Discover with us through our services or by licensing our technologies for use in your lab. • Unlock intracellular targets with the therapeutic potential of T cell receptor (TCR) modalities through our fully integrated Keyway™ TCRm discovery service offering. • Reach genetic disease targets at the nucleic acid level with our novel AntiClastic™ ASO Format, which enhances the molecules potency while minimizing off-target interaction and inflammatory response. • Co-build new biotechnology companies that leverage our core platforms and service capabilities with Alloys affiliated Venture Studio, 82VS. Founded in 2017 and privately funded by visionary investors, Alloy is headquartered in Boston, MA, with labs in Cambridge, U.K.; Basel, CH; and Athens, GA. We reinvest 100% of our revenue back into innovation and access to innovation. Reach out, follow, and visit our website, to learn more about how we can make better medicines, together. https://www.alloytx.com/
Experience · 7 entries
All (7)
Investments (5)
Board (5)
2021
Board Member
Aug 2021
Junípero Serra High School is an exceptional Catholic college preparatory school for boys. Serra is located in San Mateo County, in the heart of the Peninsula between San Francisco and Silicon Valley. We offer an outstanding academic program and a transformative environment for young men. We urge our students to explore their interests and share their talents by engaging in service, athletics, clubs, leadership and social activities. Our teachers and counselors are among the finest educators in the Bay Area. They work tirelessly to ensure that each student receives the support he needs to achieve his personal best. Serra teachers know how to bring out the best in each student. Every year, 100% of Serra graduates are accepted to colleges and universities in California and across the country. With a proven record of athletic success and a rich tradition of strong athletic competition, championships, sportsmanship and teamwork, our athletics program is a source of pride for the entire Serra community. Our coaches are dedicated to developing men of integrity and leadership. Serra offers the proven benefits of single-gender education with important coeducational opportunities. The popular Tri-School Program is a valuable partnership with Serra and our sister schools, Notre Dame and Mercy. Students from all three schools share academic, cultural and social experiences in classes, clubs, retreats, dances, events, and music and drama productions on all three campuses. The Tri-School Program offers the best of both worlds. Serra graduates are part of a lifelong brotherhood based on faith, wisdom, service, community and leadership.
Board Member
Aug 2021
BioAge is a clinical-stage biopharmaceutical company developing therapeutic product candidates for metabolic diseases by targeting the biology of human aging. The Companys lead product candidate, BGE-102, is a potent, orally available, brain-penetrant small-molecule NLRP3 inhibitor being developed for cardiovascular risk and retinal diseases. A Phase 1 SAD/MAD trial of BGE-102 is underway, with topline data including additional MAD cohorts anticipated in 1H26. The Company is also developing long-acting injectable and oral small molecule APJ agonists for obesity. BioAge’s additional preclinical programs, which leverage insights from the Company’s proprietary discovery platform built on human longevity data, address key pathways involved in metabolic aging. BioAge offers a comprehensive compensation package, comprehensive health and wellness benefits (medical, dental, and vision insurance), childcare and fertility benefits, and a 401(k) retirement savings plan with matched employer contributions. We pride ourselves on giving employees many opportunities for career development, including a generous annual budget for continued learning and dedication to training and skill development. At BioAge, everyone matters, and we embrace diversity and differences while we learn from each other. We are an equal opportunity employer. BioAge prohibits discrimination and harassment of any type and affords equal employment opportunities to employees and applicants without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. BioAge conforms to the spirit as well as the letter of all applicable laws and regulations.
2020
Board Member
Oct 2020
Founded in 1950, St. Anthony's provides medical care, addiction recovery treatment, workforce development, jobs, meals, clothing and tech access to those experiencing homelessness and low-income people in the Franciscan spirit.
2019
Limited Partner, Investment Advisor
Jun 2019
Early stage venture firm focused on life science discoveries to prevent, detect and cure disease.
Board Member
May 2019
Developing next generation mRNA immunotherapies
Show all 7 entries ↓
Investment activity
2018–2021 · 5 investments
20181201912020120212
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