Daniel Bertholet — investor profile photo

Daniel Bertholet

Founder & Partner at 4see ventures

📍 Geneva, Geneva, Switzerland🔄 Updated November 2026💼 3 investments📅 30 years investing🗓 Last invested Jun 2020
Operator-angel🌍 Switzerland
3
Total investments
1
Early stage
0
Mid stage
0
Late stage
30y
Years active

Portfolio

2 investments · sorted by recency
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Board Observer
Jun 2020
HAYA Therapeutics is a precision medicines company developing RNA-guided programmable therapeutics targeting the regulatory genome for serious health conditions including cardiovascular disease and cancer. The company is using its innovative cell-state modifying platform to gain novel insights into the biology of long non-coding RNAs (lncRNAs), the ‘dark genomes’ information processing features and ‘source code’. HAYA’s lead therapeutic candidate is HTX-001, an antisense oligonucleotide targeting Wisper, which is a tissue and cell-specific cardiac lncRNA known to play a role in heart failure. The company is also developing a pipeline of lncRNA-targeting candidates for the cell-specific treatment of diseases in other tissues, including the lungs and the microenvironment of solid tumor cancers. Headquartered at the life sciences park Biopôle in Lausanne, Switzerland with laboratory facilities at JLABS @ San Diego, HAYA is led by a world-class team of experts in programmable and precision RNA-targeted therapeutics and is supported by a strong investor consortium. HAYA’s mission is to identify and develop breakthrough disease-modifying therapeutics with the potential for greater efficacy, safety, and accessibility than existing treatments.
Board Member
Jan 2020
LumiThera, Inc. is an ophthalmic medical device company that is Harnessing the Power of Light™ to offer a comprehensive approach for detecting, treating, and monitoring retinal diseases, specifically dry age-related macular degeneration (AMD). LumiThera is the leader in ophthalmic photobiomodulation (PBM) innovation with its flagship product, the Valeda® Light Delivery System. Multiwavelength Valeda treatments are for patients suffering from dry AMD. Valeda is FDA Authorized in the US, CE Marked in the EU, and available in select countries in Latin America. AdaptDx Pro® is a portable dark adaptometer that utilizes AI to deliver a uniform patient experience. AdaptDx Pro is available in the U.S. and Canada. NOVA Vision Testing System is a comprehensive electrophysiology platform that provides objective assessment of the entire pathway for visual and neuro-visual disorders. VEP is available in the U.S. and select countries outside of the U.S. ERG is only available outside of the U.S. For more information on Valeda, visit www.lumithera.com. AdaptDx Pro and NOVA are available through LumiThera Diagnostics, Inc. and Diopsys, Inc., respectively.
Experience · 9 entries
All (9)
Investments (3)
Founder (1)
Board (2)
2020
Board Observer
Jun 2020
HAYA Therapeutics is a precision medicines company developing RNA-guided programmable therapeutics targeting the regulatory genome for serious health conditions including cardiovascular disease and cancer. The company is using its innovative cell-state modifying platform to gain novel insights into the biology of long non-coding RNAs (lncRNAs), the ‘dark genomes’ information processing features and ‘source code’. HAYA’s lead therapeutic candidate is HTX-001, an antisense oligonucleotide targeting Wisper, which is a tissue and cell-specific cardiac lncRNA known to play a role in heart failure. The company is also developing a pipeline of lncRNA-targeting candidates for the cell-specific treatment of diseases in other tissues, including the lungs and the microenvironment of solid tumor cancers. Headquartered at the life sciences park Biopôle in Lausanne, Switzerland with laboratory facilities at JLABS @ San Diego, HAYA is led by a world-class team of experts in programmable and precision RNA-targeted therapeutics and is supported by a strong investor consortium. HAYA’s mission is to identify and develop breakthrough disease-modifying therapeutics with the potential for greater efficacy, safety, and accessibility than existing treatments.
Board Member
Jan 2020
LumiThera, Inc. is an ophthalmic medical device company that is Harnessing the Power of Light™ to offer a comprehensive approach for detecting, treating, and monitoring retinal diseases, specifically dry age-related macular degeneration (AMD). LumiThera is the leader in ophthalmic photobiomodulation (PBM) innovation with its flagship product, the Valeda® Light Delivery System. Multiwavelength Valeda treatments are for patients suffering from dry AMD. Valeda is FDA Authorized in the US, CE Marked in the EU, and available in select countries in Latin America. AdaptDx Pro® is a portable dark adaptometer that utilizes AI to deliver a uniform patient experience. AdaptDx Pro is available in the U.S. and Canada. NOVA Vision Testing System is a comprehensive electrophysiology platform that provides objective assessment of the entire pathway for visual and neuro-visual disorders. VEP is available in the U.S. and select countries outside of the U.S. ERG is only available outside of the U.S. For more information on Valeda, visit www.lumithera.com. AdaptDx Pro and NOVA are available through LumiThera Diagnostics, Inc. and Diopsys, Inc., respectively.
2019
4see ventures
Managing Partner
Dec 2019
Managing Partner
Aug 2019
4see ventures is a Swiss venture capital firm investing in healthcare, biotech, medtech, digital health, tech, fintech, climate tech mainly in Switzerland. We back entrepreneurs who are disrupting their markets segments. We invest from CHF300k to CHF4.0m in early-stage, mid- and late-stage ventures.
2007
Sr. Investment Director
Jan 2007
Endeavour Vision is a leading venture capital and growth equity firm investing in commercial-stage medtech and digital health companies. We invest in transformative healthcare technologies that provide superior clinical benefits for patients or bring significant efficiencies to health systems. Our team offers strategic and operational expertise and extensive international experience investing in companies in Europe and North America. We have a proven track record of successful exits with recently realized investments that include Vertiflex (acquired by Boston Scientific in 2019), Medartis (IPO on SIX in Q1 2018) and Symetis (acquired by Boston Scientific in 2017). Endeavour Vision’s international investment teams are located in Geneva, Switzerland and Minneapolis, US.
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Investment activity
1996–2020 · 3 investments
1996120202
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