Afif Khoury

Founder & CEO at SOCi | CEO of the Year (SDBJ 2025) | Top 50 Generative AI Entrepreneurs (Great Entrepreneurs 2025) | Inc5000 x8 | Forbes Technology Counsel Member | Husband | Father x4 | Student

📍 San Diego, California, United States🔄 Updated September 2026💼 17 investments📅 13 years investing🗓 Last invested Oct 2022𝕏 @upgrade_to_unlock
VC🌍 United States
17
Total investments
6
Early stage
3
Mid stage
4
Late stage
13y
Years active

Portfolio

13 investments · sorted by recency
All investments
Early stage
Mid stage
Late stage
Investor
Oct 2022
Moove is a global mobility company building the operating layer for autonomous mobility. Headquartered in the UAE and founded in 2020 by Ladi Delano and Jide Odunsi, Moove finances, owns and operates productive mobility assets for leading mobility platforms across manned and autonomous transportation. Moove operates across 13 countries and 29 cities, with approximately 42,000 vehicles and more than 3,300 employees worldwide. The company recently closed a $250million Series C round scaled rapidly to an ARR of $420m within 5 years of launch.
Board Member
Jun 2022
Lawmatics is the #1 automation platform for law firms, offering legal client intake, CRM, marketing automation, billing, and much more, all in one easy-to-use software. With Lawmatics, law firms streamline their operations, impress clients, and win more business. To learn more, visit www.lawmatics.com.
Investor
Jun 2022
SEW AI Powered Energy & Utilities Industry Innovative Digital Customer Experiences (CX) + Workforce Experiences (WX) + Intelligent Experience (iX) Cloud Platforms to Engage, Empower, and Educate billions of people to save energy and water. We partner with Industry to deliver AI Platforms that are easy-to-use, integrate seamlessly, and help build a strong technology foundation that allows them to become future ready.
Investor
Feb 2021
Deako believes that everyone should be able to enjoy the wonderful experiences of personalized lighting. We invented the worlds first plug-n-play light switch, giving homeowners maximum flexibility to customize their systems, at any time, in minutes and without turning off the power. Deako’s beautiful designer switches are like nothing else on the market today. Deako Lighting has been named the #1 Smart Lighting Control System by TecHome Builder, Top 25 Innovative IOT Companies by Entrepreneur, featured in “I Want That!” episode on DIY Network, Top 50 most promising Startups by Bloomberg, and “Changing The Way Builders Spec Light Switches” - Builder Magazine.
Investor
Jun 2019
At Cradle Genomics, our mission is to provide knowledge that helps every pregnancy. We're dedicated to the transformation of non-invasive prenatal testing (NIPT) by offering the most comprehensive fetal genetic analysis and pregnancy health screening solutions at the earliest stages of pregnancy. Cradle Genomics is newly formed with our headquarters based in San Diego. Cradle tests are based on the genetic analysis of fetal cells quickly collected during a first trimester visit with no risk to the mother or developing fetus. We are passionate about improving patient care and enabling global access to the best possible prenatal solutions. For additional information please contact us at info@cradlegenomics.com.
Investor
Oct 2018
Aspen is developing induced-pluripotent stem cells (iPSCs) to address diseases with high unmet medical need, beginning with autologous neuron replacement for Parkinson’s disease (PD) and extending across the brain and affected organs.
Investor (acq by Merck)
Sep 2018
VelosBio is a clinical-stage biopharmaceutical company committed to developing novel, first-in-class, ROR1-directed therapeutics to transform the lives of patients with cancer.
early stageBiotechnology
Investor
Dec 2016
Oncternal Therapeutics is a clinical-stage oncology company developing a diverse pipeline of treatments for cancers with critical unmet medical need. Oncternal focuses drug development on promising yet untapped biological pathways implicated in cancer progression. The pipeline includes cirmtuzumab, a monoclonal antibody in Phase 1/2 development that inhibits the ROR1 receptor in various hematologic cancers; TK-216, a small-molecule in Phase 1 development that inhibits ETS-family oncoproteins, as a treatment for Ewing sarcoma, a rare pediatric cancer; and a CAR-T therapy that targets ROR1 currently in preclinical development as a potential treatment for solid tumors and hematologic cancers. Based in San Diego, Oncternal is committed to advancing its pipeline rapidly and efficiently to bring patients a new wave of first-in-class cancer treatments.
mid stageBiotechnology
Investor (IPO)
Nov 2016
Singular Genomics is inventing at the forefront of genomics, one of the world’s fastest-growing industries. We are a publicly traded life science technology company that is leveraging novel, next-generation sequencing (NGS) and multi-omics technologies to build products that empower researchers and clinicians. The G4 Sequencing Platform, our first commercially available product, is a powerful, highly versatile benchtop genomic sequencer designed to produce fast and accurate results. In development, the PX system leverages Singular’s proprietary sequencing technology, applying it as an in-situ readout to look at RNA and proteins in single cells and tissue. We are committed to unlocking the potential of our core technologies to reshape the future of genomics. We offer a dynamic, fast-paced, results-oriented environment where employees can make a significant impact in a rapidly expanding company. Innovation, continuous learning, multi-disciplinary collaboration, and diversity of thought are pillars of our culture.
Investor
Dec 2014
Obalon is an engineering-driven medical technology company with a singular focus on innovative, high-quality gastric balloon technology. Located in San Diego, California, the technical team at Obalon has a long history of working closely with leading clinicians to develop innovative medical products that revolutionize treatment of chronic disease.
Investor
Aug 2014
Epic Sciences, Inc. is developing novel diagnostics to personalize and advance the treatment and management of cancer. Epic’s mission is to enable the rapid and non-invasive detection of genetic and molecular changes in cancer throughout a patient’s journey. The company was founded on a powerful platform to identify and characterize rare cells, including circulating tumor cells (CTCs). Our technology helps match patients to targeted therapies and monitor for drug resistance, so that the best treatment path can be chosen at every clinical decision point. Today, we partner with leading pharmaceutical companies and major cancer centers around the world. Epic’s goal is to commercialize our technology to increase the success rate of cancer drugs in clinical trials and improve patient outcomes by providing physicians with real-time information to guide treatment choices. For more information please contact us at info@epicsciences.com
Investor
Jul 2014
Based in San Diego and founded in 2013, Omniome is a biotechnology company developing a proprietary DNA sequencing platform capable of delivering unsurpassed sequencing accuracy. Backed by leading life sciences venture investors and a proven management team, Omniome’s vision is to be the most trusted DNA sequencing platform and leader in clinical sequencing. We are a quality-focused, start-up environment where development thrives. Our culture is inspiring, fun and consists of a talented team of individuals who propose innovative ideas keeping collaboration a top priority.
Former Investor, Board Observer (acq)
Jun 2014
Based in San Diego and founded in 2013, Edico Genome Inc. develops cutting edge solutions that power the genomic revolution. Our vision is to revolutionize genome sequencing analysis by providing unprecedented speed, scale and accuracy. The “Big Data” Problem: As DNA sequencing costs have plummeted over the last few years, furthered by Illumina’s recent announcement of the ability to sequence genomes for below $1,000, raw data generated by sequencing has increased exponentially, measuring petabytes of data, making analyses and transfer of all this data difficult. These large amounts of data produce a critical bottleneck in the DNA sequencing workflow that has previously only been addressable by throwing increasing numbers of ever more powerful CPU cores at the problem. However, since the data being produced by sequencing already far outpaces Moore’s Law, this solution has very limited sustainability. DRAGEN™ Bio-IT Processor To address this problem, Edico Genome is developing the DRAGEN™ Bio-IT Processor, the world’s first Next Generation Sequencing (NGS) bioinformatics reconfigurable processor. It enables the computational time required for the NGS data analysis pipeline to be radically reduced from many hours down to only a few minutes. The mapping, alignment, sorting and variant calling that is currently performed by software on extensive cluster or cloud-based platforms, is performed at a fraction of the computing cost by DRAGEN - without compromising accuracy. Our patent-pending technology makes it faster, easier and cheaper to work with NGS data and to discover links between DNA sequence variations and human disease.
early stageBiotechnology
Experience · 24 entries
All (24)
Investments (17)
Founder (3)
Board (2)
2022
Investor
Oct 2022
Moove is a global mobility company building the operating layer for autonomous mobility. Headquartered in the UAE and founded in 2020 by Ladi Delano and Jide Odunsi, Moove finances, owns and operates productive mobility assets for leading mobility platforms across manned and autonomous transportation. Moove operates across 13 countries and 29 cities, with approximately 42,000 vehicles and more than 3,300 employees worldwide. The company recently closed a $250million Series C round scaled rapidly to an ARR of $420m within 5 years of launch.
Board Member
Jun 2022
Lawmatics is the #1 automation platform for law firms, offering legal client intake, CRM, marketing automation, billing, and much more, all in one easy-to-use software. With Lawmatics, law firms streamline their operations, impress clients, and win more business. To learn more, visit www.lawmatics.com.
Investor
Jun 2022
SEW AI Powered Energy & Utilities Industry Innovative Digital Customer Experiences (CX) + Workforce Experiences (WX) + Intelligent Experience (iX) Cloud Platforms to Engage, Empower, and Educate billions of people to save energy and water. We partner with Industry to deliver AI Platforms that are easy-to-use, integrate seamlessly, and help build a strong technology foundation that allows them to become future ready.
2021
Investor
Feb 2021
Deako believes that everyone should be able to enjoy the wonderful experiences of personalized lighting. We invented the worlds first plug-n-play light switch, giving homeowners maximum flexibility to customize their systems, at any time, in minutes and without turning off the power. Deako’s beautiful designer switches are like nothing else on the market today. Deako Lighting has been named the #1 Smart Lighting Control System by TecHome Builder, Top 25 Innovative IOT Companies by Entrepreneur, featured in “I Want That!” episode on DIY Network, Top 50 most promising Startups by Bloomberg, and “Changing The Way Builders Spec Light Switches” - Builder Magazine.
2019
Investor
Jun 2019
At Cradle Genomics, our mission is to provide knowledge that helps every pregnancy. We're dedicated to the transformation of non-invasive prenatal testing (NIPT) by offering the most comprehensive fetal genetic analysis and pregnancy health screening solutions at the earliest stages of pregnancy. Cradle Genomics is newly formed with our headquarters based in San Diego. Cradle tests are based on the genetic analysis of fetal cells quickly collected during a first trimester visit with no risk to the mother or developing fetus. We are passionate about improving patient care and enabling global access to the best possible prenatal solutions. For additional information please contact us at info@cradlegenomics.com.
Show all 24 entries ↓
Investment activity
2013–2022 · 17 investments
20131201442016320184201912021120223
Recent (last 2 years)Earlier