Intrinsic Therapeutics, Inc

📍 Woburn, United States🗓 Founded 2000👥 82 employees💰 Last funded Jun 2021
Adjacent to a lumbar discectomy, the Barricaid® device is designed to close large defects in the annulus, which often lead to disc reherniation and/or disc collapse. Barricaid is a permanent implant with two components - a titanium bone anchor and a flexible polymer barrier. The barrier is designed to prevent reherniation by physically blocking the annulus at the post-surgery defect. The anchor component is comprised of titanium alloy that is placed into either the caudal or cranial-adjacent vertebral body to secure the device in position. The Barricaid has been studied in a definitive – level 1B evidence - randomized superiority trial with over 550 patients enrolled (clinicaltrials.gov NCT01283438). The study focuses on patient at highest risk of reherniation and reoperation, enrolling only those patients with large defects (width >5 mm). The co-primary endpoints of reherniation and an 8-point composite of safety and effectiveness are evaluated at 2 years, with a parallel cost effectiveness analysis. Treated patients were found superior on both endpoints, with significantly lower rates of symptomatic recurrences (12% vs. 25%, p<0.001), index-level reoperations (9% vs. 16%, p=0.01), and device or procedure related serious adverse events (SAEs) (7% vs. 17%, p=0.001). Through two years, a total of 29 reoperations were performed in Barricaid subjects in comparison to 61 procedures in Controls. Study results are published in The Spine Journal, May 2018. Barricaid is FDA-Approved For full risk/benefit, see: www.barricaid.com/instructions-for-use
2
Total investors
1
Early stage
0
Mid stage
0
Late stage
2000
Founded
Investor geography1 country
United States
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Frequently asked questions
Who invested in Intrinsic Therapeutics, Inc?
Intrinsic Therapeutics, Inc has 2 investors on record on gritt.io, including 1 early-stage backers.
When did Intrinsic Therapeutics, Inc last raise funding?
The most recent investment in Intrinsic Therapeutics, Inc recorded on gritt.io was in June 2021.
When was Intrinsic Therapeutics, Inc founded?
Intrinsic Therapeutics, Inc was founded in 2000.
What industry is Intrinsic Therapeutics, Inc in?
Intrinsic Therapeutics, Inc operates in Medical Equipment Manufacturing. Find similar Medical Equipment Manufacturing investors on gritt.io.
Where is Intrinsic Therapeutics, Inc based?
Intrinsic Therapeutics, Inc is headquartered in Woburn, United States.